PDE8A - phosphodiesterase 8A Gene

Species: Canis lupus familiaris (sub-species: familiaris)

Gene Type: protein coding
Gene ID: 488752

About PDE8A

Primary_assembly 3: 54,631,028-54,787,190 forward strand.ROS_Cfam_1.0:CM025102.1

This gene has 7 transcripts (splice variants), 219 orthologues and 22 paralogues.

PDE8A Products (4)

mRNA Protein Name
XM_038661427.1 XP_038517355.1 high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X4
XM_038661424.1 XP_038517352.1 high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X1
XM_038661426.1 XP_038517354.1 high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X3
XM_038661425.1 XP_038517353.1 high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X2

PDE8A Protein Structure

PDE8

PDE8: cl07304 (0 - 58)

OmpR

OmpR: cl34028 (85 - 172)

PAS_9

PAS_9: pfam13426 (229 - 327)

PDEase_I

PDEase_I: pfam00233 (558 - 814)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 838 a.a.
Protein Preferred Names Protein Names

high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-15426 PF-04957325 Inhibitor 99.55% Unkown
HY-134937 BC8-15 Inhibitor / Unkown
HY-179503 PDE/TRPA1/CHIT1-IN-1 Inhibitor / Unkown
HY-RS10242 PDE8A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS10243 Pde8a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS10244 Pde8a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens PDE8A NCBI NCBI:5151