2. Gene
  3. Gucy1a1 - guanylate cyclase 1 soluble subunit alpha 1 Gene

Gucy1a1 - guanylate cyclase 1 soluble subunit alpha 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as SGC; Gucy1a3

Gene ID: 497757 | Gene type: protein coding

About Gucy1a1

Summary

Enables ion binding activity. Contributes to Adenylate Cyclase activity and cytidylate cyclase activity. Involved in response to Herbicide and response to organic cyclic compound. Part of Guanylate Cyclase complex, soluble. Human ortholog(s) of this gene implicated in Moyamoya disease. Orthologous to human GUCY1A1 (Guanylate Cyclase 1 soluble subunit alpha 1). [provided by Alliance of Genome Resources, Apr 2022]

Gucy1a1 Products(1)

mRNA Protein Name
NM_017090.2 NP_058786.2 guanylate cyclase soluble subunit alpha-1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
contributes to adenylate cyclase activity IDA
IDA: Inferred from direct assay
22122229 RGD
contributes to cytidylate cyclase activity IDA
IDA: Inferred from direct assay
22122229 RGD
enables nitric oxide binding IDA
IDA: Inferred from direct assay
17098738 RGD
enables protein-containing complex binding IDA
IDA: Inferred from direct assay
17098738 RGD
Biological Process GO Annotation Evidence Reference Source
involved in response to herbicide IEP
IEP: Inferred from expression pattern
20388547 RGD
involved in response to organic cyclic compound IEP
IEP: Inferred from expression pattern
19025659 RGD
Cellular Component GO Annotation Evidence Reference Source
part of guanylate cyclase complex, soluble IDA
IDA: Inferred from direct assay
17098738 RGD
part of protein-containing complex IDA
IDA: Inferred from direct assay
16024662 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

guanylate cyclase soluble subunit alpha-1

GCS-alpha-1

GCS-alpha-3

Guanylate cyclase, soluble, alpha 1 (GTP pyrophosphate - lyase)

guanylate cyclase 1 soluble subunit alpha 3

guanylate cyclase 1, soluble, alpha 3

guanylate cyclase soluble subunit alpha-3

soluble guanylate cyclase large subun

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05918 GUCY1A1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS05920 GUCY1B1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gucy1a1 NCBI NCBI:2982