Akap11 - A-kinase anchoring protein 11 Gene

Rattus norvegicus

Also known as Akap

Gene ID: 498549 | Gene type: protein coding

About Akap11

Summary

Enables kinase regulator activity; protein kinase A binding activity; and protein Phosphatase 1 binding activity. Involved in positive regulation of establishment of endothelial barrier and positive regulation of protein phosphorylation. Located in peroxisome. Part of protein-containing complex. Orthologous to human AKAP11 (A-kinase anchoring protein 11). [provided by Alliance of Genome Resources, Apr 2022]

Akap11 Products(1)

mRNA	Protein	Name
NM_001394793.1	NP_001381722.1	A-kinase anchor protein 11

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables kinase regulator activity	IDA IDA: Inferred from direct assay	12147701	RGD
enables protein kinase A catalytic subunit binding	IDA IDA: Inferred from direct assay	8621616	RGD
enables protein kinase A regulatory subunit binding	IDA IDA: Inferred from direct assay	8621616	RGD
enables protein phosphatase 1 binding	IDA IDA: Inferred from direct assay	10209101	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in positive regulation of establishment of endothelial barrier	IMP IMP: Inferred from mutant phenotype	25188285	RGD
involved in positive regulation of protein phosphorylation	IMP IMP: Inferred from mutant phenotype	18385542	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in peroxisome	IDA IDA: Inferred from direct assay	8621616	RGD
part of protein-containing complex	IDA IDA: Inferred from direct assay	8621616	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

A-kinase anchor protein 11

A kinase (PRKA) anchor protein 11	A-kinase anchor protein 220 kDa
A-kinase anchoring protein 220, AKAP 220	AKAP 220
AKAP-11	PRKA11
protein kinase A-anchoring protein 11

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00514	AKAP11 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Akap11	NCBI	NCBI:11215

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