2. Gene
  3. AKAP11 - A-kinase anchoring protein 11 Gene

AKAP11 - A-kinase anchoring protein 11 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as PRKA11; AKAP-11; AKAP220; PPP1R44

Gene ID: 11215 | Gene type: protein coding

About AKAP11

Cytogenetic location: 13q14.11 Genomic coordinates (GRCh38): 13:42,271,477-42,323,261 (from NCBI)

This gene has 1 transcript (splice variant), 201 orthologues and 3 paralogues. Ubiquitous expression in brain (RPKM 22.2), testis (RPKM 15.0) and 24 other tissues.

Summary

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed at high levels throughout spermatogenesis and in mature sperm. It binds the RI and RII subunits of PKA in testis. It may serve a function in cell cycle control of both somatic cells and germ cells in addition to its putative role in spermatogenesis and sperm function. [provided by RefSeq, Jul 2008]

AKAP11 Products(1)

mRNA Protein Name
NM_016248.4 NP_057332.1 A-kinase anchor protein 11
Protein Preferred Names Protein Names

A-kinase anchor protein 11

A kinase (PRKA) anchor protein 11

Related Diseases

Diseases Alias
Retinitis Pigmentosa 48

RP48

Retinitis Pigmentosa, Type 48
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00514 AKAP11 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris AKAP11 VGNC VGNC:37753
Mus musculus AKAP11 MGD MGI:2684060
Bos taurus AKAP11 VGNC VGNC:25781
Felis catus AKAP11 VGNC VGNC:59712
Macaca mulatta AKAP11 VGNC VGNC:69765
Rattus norvegicus AKAP11 RGD RGD:2079