Dact1 - dishevelled-binding antagonist of beta-catenin 1 Gene

Predicted to enable several functions, including beta-catenin binding activity; delta-catenin binding activity; and enzyme binding activity. Predicted to be involved in several processes, including negative regulation of JNK cascade; negative regulation of beta-catenin-TCF complex assembly; and regulation of Wnt signaling pathway. Predicted to act upstream of or within several processes, including dendrite morphogenesis; positive regulation of fat cell differentiation; and positive regulation of protein catabolic process. Predicted to be located in nucleoplasm. Predicted to be part of beta-catenin destruction complex. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in Townes-Brocks syndrome. Orthologous to human DACT1 (dishevelled binding antagonist of beta catenin 1). [provided by Alliance of Genome Resources, Apr 2022]