SPRN - shadow of prion protein Gene

Also Known as SHO; SHADOO; bA108K14.1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 503542

About SPRN

Cytogenetic location: 10q26.3 Genomic coordinates (GRCh38): 10:133,420,666-133,424,625 (from NCBI)

This gene has 2 transcripts (splice variants) and 60 orthologues. Ubiquitous expression in brain (RPKM 10.6), duodenum (RPKM 4.2) and 25 other tissues.

Summary

Predicted to enable nucleic acid binding activity. Predicted to be involved in protein import into nucleus. Predicted to be located in membrane. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

SPRN Products (2)

mRNA Protein Name
NM_001012508.6 NP_001012526.2 shadow of prion protein precursor
NM_001391974.1 NP_001378903.1 shadow of prion protein precursor

SPRN Protein Structure

Shadoo

Shadoo: Shadow of prion protein, neuroprotective (19 - 151)

  • 0
  • 100
  • 151 a.a.
Protein Preferred Names Protein Names

shadow of prion protein

  • hypothetical protein BC004409

Related Diseases

Diseases Alias
Scrapie
Prion Disease

  • Spongiform Encephalopathy

  • Transmissible Spongiform Encephalopathies

  • Prion Diseases

  • Prion Disease Pathway

  • Transmissible Spongiform Encephalopathy

  • Prion Induced Disorder

  • Prion Protein Disease

  • Inherited Human Transmissible Spongiform Encephalopathies

  • Prion Protein Diseases

  • Prion-Associated Disorders

  • Prion-Induced Disorders

  • Transmissible Dementias

  • Tses

  • Human Prion Disease

  • Tse

  • Encephalopathy, Transmissible Spongiform

  • Prion Disease, Susceptibility To

  • Spongiform Encephalopathies

  • Human Transmissible Spongiform Encephalopathies, Inherited
Creutzfeldt-Jakob Disease

  • Variant Creutzfeldt-Jakob Disease

  • CJD

  • Bovine Spongiform Encephalopathy

  • Vcjd

  • Inherited Creutzfeldt-Jakob Disease

  • Creutzfeldt-Jakob Disease, Familial

  • Creutzfeldt Jakob Disease

  • Creutzfeldt-Jacob Disease

  • Creutzfeldt Jacob Disease

  • Sporadic Creutzfeldt-Jakob Disease

  • Encephalopathy, Bovine Spongiform

  • Creutzfeldt-Jakob Disease, Variant, Resistance To

  • Creutzfeldt-Jakob Disease, Variant

  • Creutzfeldt Jacob Syndrome

  • Jakob-Creutzfeldt Disease

  • Subacute Spongiform Encephalopathy

  • Transmissible Virus Dementia

  • New Variant Of Cjd

  • Nv-Cjd

  • Variant Cjd

  • Variant Creutzfeldt-Jacob Disease

  • Sporadic Cjd

  • Inherited Cjd

  • Acquired Creutzfeldt-Jakob Disease

  • Variant Mcj

  • Encephalopathy Bovine Spongiform

  • Familial Creutzfeldt-Jakob Disease

  • Creutzfeldt-Jakob Syndrome

  • New Variant Creutzfeldt-Jakob Disease

  • Creutzfeldt-Jakob Disease, Sporadic

  • Acquired Cjd

  • Scjd - [Sporadic Creutzfeldt-Jakob Disease]

  • Idiopathic Creutzfeldt-Jakob Disease

  • Creutzfeld-Jakob Disease Nos

  • Vcjd - [Variant Creutzfeldt-Jakob Disease]
Chronic Wasting Disease

  • Wasting Disease, Chronic
Kuru

  • Kuru, Susceptibility To

  • Kuru Encephalopathy

  • Kuru Encephalitis

  • Kuru Disease
Gerstmann-Straussler Disease

  • Gerstmann-Straussler-Scheinker Disease

  • Gerstmann-Straussler-Scheinker Syndrome

  • Prion Dementia

  • Cerebral Amyloid Angiopathy, Prnp-Related

  • GSD

  • Gss

  • Cerebellar Ataxia, Progressive Dementia, And Amyloid Deposits In Cns

  • Amyloidosis, Cerebral, With Spongiform Encephalopathy

  • Subacute Spongiform Encephalopathy, Gerstmann-Straussler Type

  • Encephalopathy, Subacute Spongiform, Gerstmann-Straussler Type

  • Amyloidosis Cerebral With Spongiform Encephalopathy

  • Cerebellar Ataxia, Progressive Dementia, And Amyloid Deposits In The Central Nervous System

  • Encephalopathy Subacute Spongiform Gerstmann-Straussler Type

  • Gssd

  • Gerstmann Straussler Scheinker Syndrome

  • Cerebral Amyloidosis With Spongiform Encephalopathy

  • Subacute Spongiform Encephalopathy Gerstmann-Straussler Type

  • Gluthathione Synthetase Deficiency

  • Gerstmann Straussler Syndrome
Fatal Familial Insomnia

  • Insomnia, Fatal Familial

  • FFI

  • Familial Fatal Insomnia

  • Insomnia Familial Fatal

  • Insomnia Fatal Familial

  • Insomnia, Fatal, Familial

  • Ffi - [Fatal Familial Insomnia]
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13712 SPRN Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus SPRN VGNC VGNC:35239
Mus musculus SPRN MGD MGI:3582583
Canis familiaris SPRN VGNC VGNC:46764
Rattus norvegicus SPRN RGD RGD:1561845