Slc23a2 - solute carrier family 23 member 2 Gene

Rattus norvegicus

Also known as SVCT2

Gene ID: 50622 | Gene type: protein coding

About Slc23a2

Summary

Enables L-ascorbate:sodium symporter activity and L-ascorbic acid transmembrane transporter activity. Involved in several processes, including L-ascorbic acid transmembrane transport; cellular response to ethanol; and positive regulation of dendrite extension. Located in basal plasma membrane and cytoplasm. Is integral component of plasma membrane. Orthologous to human SLC23A2 (solute carrier family 23 member 2). [provided by Alliance of Genome Resources, Apr 2022]

Slc23a2 Products(1)

mRNA	Protein	Name
NM_017316.2	NP_059012.2	solute carrier family 23 member 2

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables L-ascorbate:sodium symporter activity	IDA IDA: Inferred from direct assay	10331392	RGD
enables L-ascorbate:sodium symporter activity	IMP IMP: Inferred from mutant phenotype	10331392	RGD
enables L-ascorbic acid transmembrane transporter activity	IDA IDA: Inferred from direct assay	18668520	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in L-ascorbic acid metabolic process	IMP IMP: Inferred from mutant phenotype	10331392	RGD
involved in L-ascorbic acid transmembrane transport	IDA IDA: Inferred from direct assay	18668520	RGD
involved in L-ascorbic acid transmembrane transport	IMP IMP: Inferred from mutant phenotype	10331392	RGD
involved in cellular response to ethanol	IEP IEP: Inferred from expression pattern	27085842	RGD
involved in positive regulation of dendrite extension	IMP IMP: Inferred from mutant phenotype	27085842	RGD
involved in response to oxidative stress	IEP IEP: Inferred from expression pattern	12887688	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in basal plasma membrane	IDA IDA: Inferred from direct assay	18668520	RGD
located in cytoplasm	IDA IDA: Inferred from direct assay	18668520	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

solute carrier family 23 member 2

Na(+)/L-ascorbic acid transporter 2	sodium-coupled ascorbic acid transporter 2
sodium-dependent vitamin C transporter 2	solute carrier family 23 (ascorbic acid transporter), member 2
solute carrier family 23 (nucleobase transporters), member 2

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13081	SLC23A1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS13082	SLC23A2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Slc23a2	NCBI	NCBI:9962

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