2. Gene
  3. Hs6st2 - heparan sulfate 6-O-sulfotransferase 2 Gene

Hs6st2 - heparan sulfate 6-O-sulfotransferase 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as 6OST2

Gene ID: 50786 | Gene type: protein coding

About Hs6st2

Summary

Enables heparan sulfate 6-O-sulfotransferase activity. Acts upstream of or within heparan sulfate proteoglycan biosynthetic process, enzymatic modification. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in several structures, including brain; embryo mesenchyme; eye; foot bone; and urethra. Human ortholog(s) of this gene implicated in Paganini-Miozzo syndrome. Orthologous to human HS6ST2 (heparan sulfate 6-O-sulfotransferase 2). [provided by Alliance of Genome Resources, Apr 2022]

Hs6st2 Products(4)

mRNA Protein Name
NM_001077202.2 NP_001070670.1 heparan-sulfate 6-O-sulfotransferase 2 isoform 1
NM_001290467.1 NP_001277396.1 heparan-sulfate 6-O-sulfotransferase 2 isoform 3
NM_001290468.1 NP_001277397.1 heparan-sulfate 6-O-sulfotransferase 2 isoform 4 precursor
NM_015819.4 NP_056634.3 heparan-sulfate 6-O-sulfotransferase 2 isoform 2 precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables heparan sulfate 6-O-sulfotransferase activity IDA
IDA: Inferred from direct assay
12611590 MGI
Biological Process GO Annotation Evidence Reference Source
involved in heparan sulfate proteoglycan biosynthetic process IDA
IDA: Inferred from direct assay
12611590 MGI
involved in heparan sulfate proteoglycan biosynthetic process IMP
IMP: Inferred from mutant phenotype
30377379 MGI
Cellular Component GO Annotation Evidence Reference Source
is active in Golgi apparatus IDA
IDA: Inferred from direct assay
15226404 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

heparan-sulfate 6-O-sulfotransferase 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06383 HS6ST2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hs6st2 NCBI NCBI:90161