Hmgn5 - high-mobility group nucleosome binding domain 5 Gene

Mus musculus

Also known as Nsbp1; GARP45; NBP-45

Gene ID: 50887 | Gene type: protein coding

About Hmgn5

Summary

Enables chromatin binding activity. Acts upstream of or within chromatin organization; glutathione metabolic process; and regulation of transcription by RNA polymerase II. Located in nucleoplasm. Is expressed in several structures, including 1st branchial arch; genitourinary system; gut gland; hemolymphoid system gland; and musculature. Orthologous to human HMGN5 (high mobility group nucleosome binding domain 5). [provided by Alliance of Genome Resources, Apr 2022]

Hmgn5 Products(1)

mRNA	Protein	Name
NM_016710.2	NP_057919.2	high mobility group nucleosome-binding domain-containing protein 5

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables chromatin binding	IDA IDA: Inferred from direct assay	10692437	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within chromatin organization	IMP IMP: Inferred from mutant phenotype	24392144	MGI
acts upstream of or within glutathione metabolic process	IMP IMP: Inferred from mutant phenotype	24392144	MGI
acts upstream of or within regulation of transcription by RNA polymerase II	IDA IDA: Inferred from direct assay	10692437	MGI
acts upstream of or within regulation of transcription by RNA polymerase II	IMP IMP: Inferred from mutant phenotype	21278158	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in nucleoplasm	IDA IDA: Inferred from direct assay	10692437	MGI
located in nucleus	IDA IDA: Inferred from direct assay	24392144	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

high mobility group nucleosome-binding domain-containing protein 5

nucleosome binding protein 1

nucleosome binding protein 45

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS06246	HMGN5 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Hmgn5	NCBI	NCBI:79366

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