HMGN5 - high mobility group nucleosome binding domain 5 Gene

Homo sapiens

Also known as NSBP1; NBP-45

Gene ID: 79366 | Gene type: protein coding

About HMGN5

Cytogenetic location: Xq21.1 Genomic coordinates (GRCh38): X:81,113,699-81,201,913 (from NCBI)

This gene has 7 transcripts (splice variants) and 58 orthologues. Broad expression in testis (RPKM 20.5), adrenal (RPKM 4.3) and 20 other tissues.

Summary

This gene encodes a nuclear protein with similarities to the high mobility group proteins, HMG14 and HMG17, which suggests that this protein may function as a nucleosomal binding and transcriptional activating protein. [provided by RefSeq, Sep 2009]

HMGN5 Products(1)

mRNA	Protein	Name
NM_030763.3	NP_110390.1	high mobility group nucleosome-binding domain-containing protein 5

HMGN5 Protein Structure

HMG14_17

0
100
200
282 a.a.

Protein Preferred Names

Protein Names

high mobility group nucleosome-binding domain-containing protein 5

nucleosomal binding protein 1

Related Diseases

Diseases

Alias

Phosphoglycerate Dehydrogenase Deficiency

Phgdh Deficiency	3-Phosphoglycerate Dehydrogenase Deficiency
PHGDHD	3-Pgdh Deficiency
3-Phosphoglycerate Dehydrogenase Deficiency, Infantile/Juvenile Form	Phgdh Deficiency, Infantile/Juvenile Form
Deficiency, Phosphoglycerate Dehydrogenase

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS06246	HMGN5 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	HMGN5	MGD	MGI:1355295
Rattus norvegicus	HMGN5	RGD	RGD:6497694
Bos taurus	HMGN5	VGNC	VGNC:56709
Macaca mulatta	HMGN5	VGNC	VGNC:73581

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