HMGN5 - high mobility group nucleosome binding domain 5 Gene

Also Known as NSBP1; NBP-45

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 79366

About HMGN5

Cytogenetic location: Xq21.1 Genomic coordinates (GRCh38): X:81,113,699-81,201,913 (from NCBI)

This gene has 7 transcripts (splice variants) and 58 orthologues. Broad expression in testis (RPKM 20.5), adrenal (RPKM 4.3) and 20 other tissues.

Summary

This gene encodes a nuclear protein with similarities to the high mobility group proteins, HMG14 and HMG17, which suggests that this protein may function as a nucleosomal binding and transcriptional activating protein. [provided by RefSeq, Sep 2009]

HMGN5 Products (1)

mRNA Protein Name
NM_030763.3 NP_110390.1 high mobility group nucleosome-binding domain-containing protein 5

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in negative regulation of apoptotic process IMP
IMP: Inferred from mutant phenotype
20531280 GOA
involved in positive regulation of cell population proliferation IMP
IMP: Inferred from mutant phenotype
20531280 GOA
involved in positive regulation of gene expression IMP
IMP: Inferred from mutant phenotype
20531280 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

HMGN5 Protein Structure

HMG14_17

HMG14_17: HMG14 and HMG17 (2 - 96)

  • 0
  • 100
  • 200
  • 282 a.a.
Protein Preferred Names Protein Names

high mobility group nucleosome-binding domain-containing protein 5

  • nucleosomal binding protein 1

Related Diseases

Diseases Alias
Phosphoglycerate Dehydrogenase Deficiency

  • Phgdh Deficiency

  • 3-Phosphoglycerate Dehydrogenase Deficiency

  • PHGDHD

  • 3-Pgdh Deficiency

  • 3-Phosphoglycerate Dehydrogenase Deficiency, Infantile/Juvenile Form

  • Phgdh Deficiency, Infantile/Juvenile Form

  • Deficiency, Phosphoglycerate Dehydrogenase
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06246 HMGN5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus HMGN5 MGD MGI:1355295
Rattus norvegicus HMGN5 RGD RGD:6497694
Bos taurus HMGN5 VGNC VGNC:56709
Macaca mulatta HMGN5 VGNC VGNC:73581
Others HMGN5 NCBI