Exosc10 - exosome component 10 Gene

Also Known as p2; p3; p4; RRP6; PM-Scl; Pmscl2; PM/Scl-100

Species: Mus musculus

Gene Type: protein coding
Gene ID: 50912

Summary

Predicted to enable 3'-5'-exoribonuclease activity and single-stranded RNA binding activity. Acts upstream of or within dosage compensation by inactivation of X chromosome. Predicted to be located in cytosol; nucleoplasm; and transcriptionally active chromatin. Predicted to be part of nuclear exosome (RNase complex). Predicted to be active in nucleolus. Orthologous to human EXOSC10 (exosome component 10). [provided by Alliance of Genome Resources, Apr 2022]

Exosc10 Products (3)

mRNA Protein Name
NM_001355489.1 NP_001342418.1 exosome component 10 isoform 2
NM_001355490.1 NP_001342419.1 exosome component 10 isoform 3
NM_016699.3 NP_057908.2 exosome component 10 isoform 1

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within positive regulation of mRNA cis splicing, via spliceosome IMP
IMP: Inferred from mutant phenotype
16789828 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

exosome component 10

  • P100 polymyositis-scleroderma overlap syndrome associated autoantigen homolog

  • autoantigen PM/Scl 2 homolog

  • polymyositis/scleroderma autoantigen 2 homolog

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04597 EXOSC10 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Exosc10 NCBI NCBI:5394