Grb14 - growth factor receptor bound protein 14 Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 50915

Summary

Enables protein-macromolecule adaptor activity. Predicted to be involved in Insulin Receptor signaling pathway; negative regulation of Insulin Receptor signaling pathway; and negative regulation of meiotic cell cycle process involved in oocyte maturation. Predicted to act upstream of or within signal transduction. Predicted to be located in Golgi apparatus and endosome. Predicted to be active in cytoplasm and plasma membrane. Is expressed in male reproductive gland or organ; nervous system; and nucleus pulposus. Orthologous to human GRB14 (growth factor receptor bound protein 14). [provided by Alliance of Genome Resources, Apr 2022]

Grb14 Products (4)

mRNA Protein Name
NM_001412538.1 NP_001399467.1 growth factor receptor-bound protein 14 isoform 2
NM_001412539.1 NP_001399468.1 growth factor receptor-bound protein 14 isoform 3
NM_001412540.1 NP_001399469.1 growth factor receptor-bound protein 14 isoform 4
NM_016719.2 NP_057928.1 growth factor receptor-bound protein 14 isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
20890309 MGI
enables protein-macromolecule adaptor activity IDA
IDA: Inferred from direct assay
10713090 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

growth factor receptor-bound protein 14

  • GRB14 adapter protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05779 GRB14 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Grb14 NCBI NCBI:2888