SUCO - SUN domain containing ossification factor Gene

Also Known as CH1; OPT; SLP1; C1orf9

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 51430

About SUCO

Cytogenetic location: 1q24.3 Genomic coordinates (GRCh38): 1:172,532,349-172,611,833 (from NCBI)

This gene has 10 transcripts (splice variants) and 278 orthologues. Ubiquitous expression in bone marrow (RPKM 30.3), testis (RPKM 17.2) and 25 other tissues.

Summary

Predicted to be involved in positive regulation of Collagen biosynthetic process; positive regulation of osteoblast differentiation; and regulation of bone remodeling. Predicted to be located in rough endoplasmic reticulum. Predicted to be active in cytoplasm and membrane. [provided by Alliance of Genome Resources, Apr 2022]

SUCO Products (4)

mRNA Protein Name
NM_001282750.2 NP_001269679.1 SUN domain-containing ossification factor isoform 3 precursor
NM_001282751.2 NP_001269680.1 SUN domain-containing ossification factor isoform 4
NM_014283.5 NP_055098.1 SUN domain-containing ossification factor isoform 1 precursor
NM_016227.4 NP_057311.3 SUN domain-containing ossification factor isoform 2

SUCO Protein Structure

Sad1_UNC

Sad1_UNC: Sad1 / UNC-like C-terminal (323 - 452)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 1000
  • 1200
  • 1254 a.a.
Protein Preferred Names Protein Names

SUN domain-containing ossification factor

  • SUN-like protein 1

Related Diseases

Diseases Alias
Gamma Heavy Chain Disease

  • Franklin Disease

  • Franklin'S Disease

  • Gamma Heavy Chain Deposition Disease

  • Igg Heavy Chain Disease

  • Gamma-Heavy Chain Disease

  • Gamma-Hcd

  • Gamma-Chain Disease
Heavy Chain Disease

  • Hcd
Alpha Chain Disease

  • Seligmann'S Disease

  • Immunoproliferative Small Intestinal Disease
Clivus Chordoma

  • Chordoma Of Clivus
Boomerang Dysplasia

  • BOOMD

  • Boomerang-Like Skeletal Dysplasia

  • Dwarfism With Short, Bowed, Rigid Limbs And Characteristic Facies

  • Piepkorn Dysplasia

  • Dysplasia, Boomerang
Mu Chain Disease

  • Mu-Chain Disease
Febrile Seizures, Familial, 4

  • FEB4

  • Convulsions, Familial Febrile, 4

  • Familial Febrile Seizures 4

  • Familial Febrile Convulsions 4
Atelosteogenesis

  • Atelosteogenesis, Type 1
Spinocerebellar Ataxia 5

  • Spinocerebellar Ataxia Type 5

  • SCA5

  • Spinocerebellar Ataxia-5

  • Ataxia, Spinocerebellar, Type 5
Lipoid Congenital Adrenal Hyperplasia

  • Congenital Adrenal Hyperplasia

  • Congenital Lipoid Adrenal Hyperplasia Due To Star Deficency

  • Congenital Lipoid Adrenal Hyperplasia

  • Lipoid Cah

  • Lipoid Adrenal Hyperplasia

  • Adrenal Hyperplasia 1

  • Cah

  • Clah

  • LCAH

  • Adrenal Hyperplasia I

  • Lipoid Hyperplasia, Congenital, Of Adrenal Cortex With Male Pseudohermaphroditism

  • Congenital Adrenal Hyperplasia Lipoid

  • Adrenal Hyperplasia, Congenital

  • Congenital Adrenal Hyperplasia, Lipoid

  • AH1

  • Congenital Lipoid Hyperplasia Of Adrenal Cortex With Male Pseudohermaphroditism

  • Adrenal Hyperplasia Congenital

  • Hyperplasia, Adrenal, Lipoid, Congenital

  • Congenital Adrenogenital Disorders Associated With Enzyme Deficiency

  • Congenital Adrenal Cortical Hyperplasia

  • Congenital Adrenal Gland Hyperplasia

  • Congenital Adrenogenital Syndrome

  • Congenital Hyperadrenocorticism

  • Congenital Adrenogenitalism

  • Congenital Female Adrenal Pseudohermaphroditism
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14006 SUCO Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus SUCO VGNC VGNC:35459
Mus musculus SUCO MGD MGI:2138346
Macaca mulatta SUCO VGNC VGNC:78112
Canis familiaris SUCO VGNC VGNC:46969
Felis catus SUCO VGNC VGNC:65827
Rattus norvegicus SUCO RGD RGD:735185