SUCO - SUN domain containing ossification factor Gene

Homo sapiens

Also known as CH1; OPT; SLP1; C1orf9

Gene ID: 51430 | Gene type: protein coding

About SUCO

Cytogenetic location: 1q24.3 Genomic coordinates (GRCh38): 1:172,532,349-172,611,833 (from NCBI)

This gene has 10 transcripts (splice variants) and 278 orthologues. Ubiquitous expression in bone marrow (RPKM 30.3), testis (RPKM 17.2) and 25 other tissues.

Summary

Predicted to be involved in positive regulation of collagen biosynthetic process; positive regulation of osteoblast differentiation; and regulation of bone remodeling. Predicted to be located in rough endoplasmic reticulum. Predicted to be active in cytoplasm and membrane. [provided by Alliance of Genome Resources, Apr 2022]

SUCO Products(4)

mRNA	Protein	Name
NM_001282750.2	NP_001269679.1	SUN domain-containing ossification factor isoform 3 precursor
NM_001282751.2	NP_001269680.1	SUN domain-containing ossification factor isoform 4
NM_014283.5	NP_055098.1	SUN domain-containing ossification factor isoform 1 precursor
NM_016227.4	NP_057311.3	SUN domain-containing ossification factor isoform 2

SUCO Protein Structure

Sad1_UNC

0
200
400
600
800
1000
1254 a.a.

Protein Preferred Names

Protein Names

SUN domain-containing ossification factor

SUN-like protein 1

Related Diseases

Diseases

Alias

Gamma Heavy Chain Disease

Franklin Disease	Franklin'S Disease
Gamma Heavy Chain Deposition Disease	Igg Heavy Chain Disease
Gamma-Heavy Chain Disease	Gamma-Hcd
Gamma-Chain Disease

Heavy Chain Disease

Hcd

Alpha Chain Disease

Seligmann'S Disease

Immunoproliferative Small Intestinal Disease

Clivus Chordoma

Chordoma Of Clivus

Boomerang Dysplasia

BOOMD	Boomerang-Like Skeletal Dysplasia
Dwarfism With Short, Bowed, Rigid Limbs And Characteristic Facies	Piepkorn Dysplasia
Dysplasia, Boomerang

Mu Chain Disease

Mu-Chain Disease

Febrile Seizures, Familial, 4

FEB4	Convulsions, Familial Febrile, 4
Familial Febrile Seizures 4	Familial Febrile Convulsions 4

Atelosteogenesis

Atelosteogenesis, Type 1

Spinocerebellar Ataxia 5

Spinocerebellar Ataxia Type 5	SCA5
Spinocerebellar Ataxia-5	Ataxia, Spinocerebellar, Type 5

Lipoid Congenital Adrenal Hyperplasia

Congenital Adrenal Hyperplasia	Congenital Lipoid Adrenal Hyperplasia Due To Star Deficency
Congenital Lipoid Adrenal Hyperplasia	Lipoid Cah
Lipoid Adrenal Hyperplasia	Adrenal Hyperplasia 1
Cah	Clah
LCAH	Adrenal Hyperplasia I
Lipoid Hyperplasia, Congenital, Of Adrenal Cortex With Male Pseudohermaphroditism	Congenital Adrenal Hyperplasia Lipoid
Adrenal Hyperplasia, Congenital	Congenital Adrenal Hyperplasia, Lipoid
AH1	Congenital Lipoid Hyperplasia Of Adrenal Cortex With Male Pseudohermaphroditism
Adrenal Hyperplasia Congenital	Hyperplasia, Adrenal, Lipoid, Congenital
Congenital Adrenogenital Disorders Associated With Enzyme Deficiency	Congenital Adrenal Cortical Hyperplasia
Congenital Adrenal Gland Hyperplasia	Congenital Adrenogenital Syndrome
Congenital Hyperadrenocorticism	Congenital Adrenogenitalism
Congenital Female Adrenal Pseudohermaphroditism

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14006	SUCO Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	SUCO	VGNC	VGNC:35459
Mus musculus	SUCO	MGD	MGI:2138346
Macaca mulatta	SUCO	VGNC	VGNC:78112
Canis familiaris	SUCO	VGNC	VGNC:46969
Felis catus	SUCO	VGNC	VGNC:65827
Rattus norvegicus	SUCO	RGD	RGD:735185