SCARA3 - scavenger receptor class A member 3 Gene

Homo sapiens

Also known as CSR; APC7; CSR1; MSLR1; MSRL1

Gene ID: 51435 | Gene type: protein coding

About SCARA3

Cytogenetic location: 8p21.1 Genomic coordinates (GRCh38): 8:27,633,463-27,734,141 (from NCBI)

This gene has 2 transcripts (splice variants), 210 orthologues and 2 paralogues. Ubiquitous expression in endometrium (RPKM 16.5), brain (RPKM 14.0) and 23 other tissues.

Summary

This gene encodes a macrophage scavenger receptor-like protein. This protein has been shown to deplete Reactive Oxygen Species, and thus play an important role in protecting cells from oxidative stress. The expression of this gene is induced by oxidative stress. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]

SCARA3 Products(2)

mRNA	Protein	Name
NM_016240.3	NP_057324.2	scavenger receptor class A member 3 isoform 1
NM_182826.2	NP_878185.1	scavenger receptor class A member 3 isoform 2

SCARA3 Protein Structure

Collagen

0
100
200
300
400
500
606 a.a.

Protein Preferred Names

Protein Names

scavenger receptor class A member 3

cellular stress response gene protein

Related Diseases

Diseases

Alias

Hand, Foot And Mouth Disease

Vesicular Stomatitis And Exanthem

Coffin-Siris Syndrome 3

CSS3	Mrd15
Mental Retardation, Autosomal Dominant 15	Autosomal Dominant Mental Retardation 15
Coffin-Siris Syndrome, Type 3

Flinders Island Spotted Fever

Fisf	Thai Tick Typhus

Queensland Tick Typhus

Australian Tick Typhus	North Queensland Tick Typhus
Rickettsia Australis Spotted Fever

Mouth Disease

Mouth Diseases

Mouth Disorders

Osteogenesis Imperfecta, Type Ii

Vrolik Type Of Osteogenesis Imperfecta	Osteogenesis Imperfecta Type 2
OI2	Oi, Type Ii
Osteogenesis Imperfecta Congenita	Oic
Osteogenesis Imperfecta Type Ii	Lethal Osteogenesis Imperfecta
Oi Type 2	Osteogenesis Imperfecta Congenita Perinatal Lethal Form
Osteogenesis Imperfecta Congenita, Perinatal Lethal Form	Perinatal Lethal Osteogenesis Imperfecta Congenita
Perinatally Lethal Oi	Osteogenesis Imperfecta 2
Oi-Ii	Oi-Iia
Oi Type Iia	Osteogenesis Imperfecta Type Iia
Osteogenesis Imperfecta Type Ii Autosomal Dominant	Oi Type Ii
Osteogenesis Imperfecta, Dominant Perinatal Lethal

Osteogenesis Imperfecta, Type I

Osteogenesis Imperfecta Type I	OI1
Oi, Type I	Osteogenesis Imperfecta Tarda
Osteogenesis Imperfecta With Blue Sclerae	Osteogenesis Imperfecta Type 1
Adair-Dighton Syndrome	Mild Osteogenesis Imperfecta
Non-Deforming Osteogenesis Imperfecta	Oi Type 1
Van Der Hoeve Syndrome	Classic Non-Deforming Oi With Blue Sclerae
Osteogenesis Imperfecta 1	Oi-I
Osteopenic Non-Fracture Syndrome	Osteogenesis Imperfecta, Mild
Osteogenesis Imperfecta	Lobstein'S Disease

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12486	SCARA3 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	SCARA3	VGNC	VGNC:81561
Canis familiaris	SCARA3	VGNC	VGNC:45896
Rattus norvegicus	SCARA3	RGD	RGD:1309269
Felis catus	SCARA3	VGNC	VGNC:80000
Bos taurus	SCARA3	VGNC	VGNC:34322
Mus musculus	SCARA3	MGD	MGI:2444418

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