Rufy3 - RUN and FYVE domain containing 3 Gene

Also Known as Ripx; Rpipx; D5Bwg0860e; 2810428M05Rik; 6330416M07Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 52822

Summary

Involved in several processes, including positive regulation of axon extension; positive regulation of intracellular protein transport; and regulation of establishment of cell polarity. Acts upstream of or within positive regulation of axonogenesis. Located in dendrite; growth cone; and perikaryon. Is expressed in several structures, including alimentary system; eye; genitourinary system; nervous system; and skin. Orthologous to human RUFY3 (RUN and FYVE domain containing 3). [provided by Alliance of Genome Resources, Apr 2022]

Rufy3 Products (7)

mRNA Protein Name
NM_001289774.1 NP_001276703.1 protein RUFY3 isoform 1
NM_001289775.1 NP_001276704.1 protein RUFY3 isoform 2
NM_001289776.2 NP_001276705.1 protein RUFY3 isoform 3
NM_001289777.2 NP_001276706.1 protein RUFY3 isoform 3
NM_001359208.2 NP_001346137.1 protein RUFY3 isoform 4
NM_001359209.2 NP_001346138.1 protein RUFY3 isoform 5
NM_027530.4 NP_081806.1 protein RUFY3 isoform 4

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
11591653 MGI
Biological Process GO Annotation Evidence References Source
involved in actin filament organization IMP
IMP: Inferred from mutant phenotype
24720729 MGI
involved in positive regulation of axon extension IDA
IDA: Inferred from direct assay
24720729 MGI
acts upstream of or within positive regulation of axonogenesis IDA
IDA: Inferred from direct assay
24720729 MGI
involved in positive regulation of intracellular protein transport IDA
IDA: Inferred from direct assay
24720729 MGI
acts upstream of or within regulation of axonogenesis IMP
IMP: Inferred from mutant phenotype
24720729 MGI
involved in regulation of establishment of cell polarity IDA
IDA: Inferred from direct assay
24720729 MGI
Cellular Component GO Annotation Evidence References Source
located in growth cone IDA
IDA: Inferred from direct assay
24720729 MGI
located in perikaryon IDA
IDA: Inferred from direct assay
24720729 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein RUFY3

  • rap2 interacting protein x

  • singar

  • singar1

  • single axon-regulated protein 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05173 FYCO1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12345 RUFY3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rufy3 NCBI NCBI:22902