Lsr - lipolysis stimulated lipoprotein receptor Gene

Also Known as ILDR3; Lisch7

Species: Mus musculus

Gene Type: protein coding
Gene ID: 54135

Summary

Predicted to enable lipoprotein particle receptor activity and low-density lipoprotein particle binding activity. Involved in several processes, including establishment of blood-brain barrier; establishment of skin barrier; and tricellular tight junction assembly. Acts upstream of or within protein localization to tricellular tight junction. Located in plasma membrane and tricellular tight junction. Is expressed in several structures, including alimentary system; genitourinary system; limb; liver; and respiratory system. Orthologous to human LSR (lipolysis stimulated lipoprotein receptor). [provided by Alliance of Genome Resources, Apr 2022]

Lsr Products (3)

mRNA Protein Name
NM_001164184.1 NP_001157656.1 lipolysis-stimulated lipoprotein receptor isoform 2 precursor
NM_001164185.1 NP_001157657.1 lipolysis-stimulated lipoprotein receptor isoform 3 precursor
NM_017405.2 NP_059101.1 lipolysis-stimulated lipoprotein receptor isoform 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
23239027 MGI
Biological Process GO Annotation Evidence References Source
involved in epithelial structure maintenance IDA
IDA: Inferred from direct assay
23239027 MGI
involved in establishment of blood-brain barrier IMP
IMP: Inferred from mutant phenotype
25753034 MGI
involved in establishment of skin barrier IDA
IDA: Inferred from direct assay
21245199 MGI
involved in liver development IMP
IMP: Inferred from mutant phenotype
15265030 MGI
involved in protein localization to tricellular tight junction IMP
IMP: Inferred from mutant phenotype
21245199 MGI
involved in tricellular tight junction assembly IDA
IDA: Inferred from direct assay
21245199 MGI
involved in tricellular tight junction assembly IMP
IMP: Inferred from mutant phenotype
22671589 MGI
Cellular Component GO Annotation Evidence References Source
located in plasma membrane IDA
IDA: Inferred from direct assay
15265030 MGI
located in tight junction IDA
IDA: Inferred from direct assay
23239027 MGI
located in tricellular tight junction IDA
IDA: Inferred from direct assay
21245199 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

lipolysis-stimulated lipoprotein receptor

  • angulin-3

  • lipolysis stimulated receptor

  • liver-specific bHLH-Zip transcription factor

  • liver-specific gene on mouse chromosome 7 protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07865 LSR Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21285 Lsr Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27804 Lsr Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lsr NCBI NCBI:51599