Ezr - ezrin Gene

Also Known as Vil2

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 54319

Summary

Enables protein domain specific binding activity. Involved in epithelial cell differentiation and filopodium assembly. Located in several cellular components, including basolateral plasma membrane; microspike; and microvillus. Orthologous to human EZR (ezrin). [provided by Alliance of Genome Resources, Apr 2022]

Ezr Products (1)

mRNA Protein Name
NM_019357.1 NP_062230.1 ezrin

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
11457882 RGD
enables protein domain specific binding IPI
IPI: Inferred from physical interaction
17045809 RGD
enables protein-containing complex binding IPI
IPI: Inferred from physical interaction
21372499 RGD
Biological Process GO Annotation Evidence References Source
involved in epithelial cell differentiation IEP
IEP: Inferred from expression pattern
7640303 RGD
involved in filopodium assembly IMP
IMP: Inferred from mutant phenotype
21753079 RGD
Cellular Component GO Annotation Evidence References Source
located in Schwann cell microvillus IDA
IDA: Inferred from direct assay
17045809 RGD
located in T-tubule IDA
IDA: Inferred from direct assay
19028724 RGD
located in apical plasma membrane IDA
IDA: Inferred from direct assay
11457882 RGD
located in astrocyte projection IDA
IDA: Inferred from direct assay
21753079 RGD
located in basolateral plasma membrane IDA
IDA: Inferred from direct assay
11726633 RGD
located in cell body IDA
IDA: Inferred from direct assay
11461930 RGD
located in cell tip IDA
IDA: Inferred from direct assay
17061246 RGD
located in filopodium IDA
IDA: Inferred from direct assay
21753079 RGD
located in microspike IDA
IDA: Inferred from direct assay
21753079 RGD
located in microvillus membrane IDA
IDA: Inferred from direct assay
11726633 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ezrin

  • cytovillin

  • p81

  • villin-2

Ezr Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Ezr P31977 Dcc Rattus norvegicus Q63155
Anti Bait CoIP
21849478
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04623 EZR Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19860 Ezr Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26360 Ezr Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ezr NCBI NCBI:7430