Wdr72 - WD repeat domain 72 Gene

Also Known as D230040E23

Species: Mus musculus

Gene Type: protein coding
Gene ID: 546144

Summary

Acts upstream of or within enamel mineralization; extracellular matrix disassembly; and protein localization to plasma membrane. Located in endosome and nucleus. Used to study amelogenesis imperfecta hypomaturation type 2A3. Human ortholog(s) of this gene implicated in amelogenesis imperfecta hypomaturation type 2A3. Orthologous to human WDR72 (WD repeat domain 72). [provided by Alliance of Genome Resources, Apr 2022]

Wdr72 Products (2)

mRNA Protein Name
NM_001033500.4 NP_001028672.2 WD repeat-containing protein 72 isoform 1
NM_001411342.1 NP_001398271.1 WD repeat-containing protein 72 isoform 2

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within ameloblast differentiation IMP
IMP: Inferred from mutant phenotype
35181734 MGI
acts upstream of or within amelogenesis IMP
IMP: Inferred from mutant phenotype
35181734 MGI
acts upstream of or within enamel mineralization IMP
IMP: Inferred from mutant phenotype
25008349 MGI
acts upstream of or within endocytosis IMP
IMP: Inferred from mutant phenotype
35181734 MGI
acts upstream of or within extracellular matrix disassembly IMP
IMP: Inferred from mutant phenotype
26247047 MGI
acts upstream of or within extracellular matrix organization IMP
IMP: Inferred from mutant phenotype
35181734 MGI
acts upstream of or within gene expression IMP
IMP: Inferred from mutant phenotype
35181734 MGI
acts upstream of or within microtubule polymerization IMP
IMP: Inferred from mutant phenotype
35181734 MGI
acts upstream of or within phosphatidylinositol 3-kinase/protein kinase B signal transduction IMP
IMP: Inferred from mutant phenotype
35181734 MGI
acts upstream of or within protein import IMP
IMP: Inferred from mutant phenotype
35181734 MGI
acts upstream of or within protein localization IMP
IMP: Inferred from mutant phenotype
35181734 MGI
acts upstream of or within protein localization to plasma membrane IMP
IMP: Inferred from mutant phenotype
26247047 MGI
acts upstream of or within regulation of pH IMP
IMP: Inferred from mutant phenotype
35181734 MGI
acts upstream of or within ruffle organization IMP
IMP: Inferred from mutant phenotype
35181734 MGI
acts upstream of or within tubulin complex assembly IMP
IMP: Inferred from mutant phenotype
35181734 MGI
acts upstream of or within vesicle organization IMP
IMP: Inferred from mutant phenotype
35181734 MGI
acts upstream of or within vesicle-mediated transport IMP
IMP: Inferred from mutant phenotype
35181734 MGI
Cellular Component GO Annotation Evidence References Source
located in endosome IDA
IDA: Inferred from direct assay
25008349 MGI
located in nucleus IDA
IDA: Inferred from direct assay
31336344 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

WD repeat-containing protein 72

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15793 WDR72 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Wdr72 NCBI NCBI:256764