ZNF280D - zinc finger protein 280D Gene

Also Known as SUHW4; ZNF634

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 54816

About ZNF280D

This gene has 13 transcripts (splice variants), 130 orthologues and 28 paralogues. Ubiquitous expression in ovary (RPKM 5.7), endometrium (RPKM 5.4) and 25 other tissues.

Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription, DNA-templated. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

ZNF280D Products (5)

mRNA	Protein	Name
NM_001002843.3	NP_001002843.1	zinc finger protein 280D isoform 2
NM_001002844.3	NP_001002844.1	zinc finger protein 280D isoform 3
NM_001288588.2	NP_001275517.1	zinc finger protein 280D isoform 1
NM_001288589.2	NP_001275518.1	zinc finger protein 280D isoform 3
NM_017661.4	NP_060131.2	zinc finger protein 280D isoform 1

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	References	Source
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ZNF280D Protein Structure

DUF4195

0
200
400
600
800
979 a.a.

Protein Preferred Names	Protein Names
zinc finger protein 280D	suppressor of hairy wing homolog 4

Related Diseases

Diseases	Alias
Borderline Glaucoma	Preglaucoma
Intellectual Developmental Disorder, X-Linked 109	Fraxe Syndrome Fragile Xe Syndrome Mental Retardation, X-Linked, Fraxe Type XLID109 Mrx109 Mental Retardation, X-Linked, Associated With Fragile Site Fraxe Fraxe Mental Retardation Syndrome X-Linked Intellectual Developmental Disorder 109 Fraxe Intellectual Disability Fraxe Mental Retardation, X-Linked 109 Fragile Site On Chromosome Xq28 Fragile Site, Folic Acid Type X-Linked Intellectual Disability Associated With Fragile Site Fraxe Fraxe Intellectual Deficit Intellectual Disability Associated With Fragile Site Fraxe
Dyslexia

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS16119	ZNF280D Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	ZNF280D	MGD	MGI:2384583
Macaca mulatta	ZNF280D	VGNC	VGNC:99350
Felis catus	ZNF280D	VGNC	VGNC:80787
Canis familiaris	ZNF280D	VGNC	VGNC:49825
Bos taurus	ZNF280D	VGNC	VGNC:52851
Rattus norvegicus	ZNF280D	RGD	RGD:1560796
Others	ZNF280D	NCBI