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SLC22A15 - solute carrier family 22 member 15 Gene

Also Known as FLIPT1; PRO34686

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 55356

About SLC22A15

Cytogenetic location: 1p13.1 Genomic coordinates (GRCh38): 1:115,976,513-116,070,054 (from NCBI)

This gene has 3 transcripts (splice variants), 188 orthologues and 22 paralogues. Broad expression in bone marrow (RPKM 6.8), skin (RPKM 3.1) and 19 other tissues.

Summary

Organic ion transporters, such as SLC22A15, transport various medically and physiologically important compounds, including pharmaceuticals, toxins, Hormones, neurotransmitters, and cellular metabolites. These transporters are also referred to as amphiphilic solute facilitators (ASFs).[supplied by OMIM, Apr 2004]

SLC22A15 Products (1)

mRNA	Protein	Name
NM_018420.3	NP_060890.2	solute carrier family 22 member 15

Gene Ontology

Molecular Function
Cellular Component

Molecular Function GO Annotation	Evidence	References	Source
enables amino-acid betaine transmembrane transporter activity	IDA IDA: Inferred from direct assay	33124720	GOA

Cellular Component GO Annotation	Evidence	References	Source
located in plasma membrane	IDA IDA: Inferred from direct assay	33124720	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SLC22A15 Protein Structure

Sugar_tr

0
100
200
300
400
500
547 a.a.

Protein Preferred Names	Protein Names
solute carrier family 22 member 15	flipt 1

Related Diseases

Diseases	Alias
Carnitine Deficiency, Systemic Primary	Carnitine Uptake Defect Renal Carnitine Transport Defect Systemic Primary Carnitine Deficiency CDSP Systemic Carnitine Deficiency Carnitine Transporter Deficiency Cud Primary Carnitine Deficiency Carnitine Uptake Deficiency Carnitine Deficiency, Systemic, Due To Defect In Renal Reabsorption Of Carnitine Carnitine Deficiency, Primary Systemic Primary Carnitine Deficiency Disease Deficiency Of Plasma-Membrane Carnitine Transporter Scd Carnitine Transporter, Plasma-Membrane, Deficiency Of Carnitine Transport Defect Carnitine Plasma-Membrane Transporter Deficiency Carnitine Transporter Defect Spcd
Adams-Oliver Syndrome	Adams Oliver Syndrome Aos Congenital Scalp Defects With Distal Limb Reduction Anomalies Aplasia Cutis Congenita With Terminal Transverse Limb Defects Congenital Scalp Defects With Distal Limb Anomalies Limb, Scalp And Skull Defects Limb Scalp And Skull Defects Absence Defect Of Limbs, Scalp, And Skull

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13068	SLC22A15 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	SLC22A15	RGD	RGD:1311184
Macaca mulatta	SLC22A15	VGNC	VGNC:77526
Mus musculus	SLC22A15	MGD	MGI:3607704
Canis familiaris	SLC22A15	VGNC	VGNC:46276
Felis catus	SLC22A15	VGNC	VGNC:65240
Bos taurus	SLC22A15	VGNC	VGNC:34723