VEZT - vezatin, adherens junctions transmembrane protein Gene

Also Known as VEZATIN

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 55591

About VEZT

Cytogenetic location: 12q22 Genomic coordinates (GRCh38): 12:95,217,807-95,302,799 (from NCBI)

This gene has 40 transcripts (splice variants) and 208 orthologues. Ubiquitous expression in thyroid (RPKM 16.2), placenta (RPKM 10.3) and 25 other tissues.

Summary

This gene encodes a transmembrane protein which has been localized to adherens junctions and shown to bind to Myosin VIIA. Examination of expression of this gene in gastric Cancer tissues have shown that expression is decreased which appears to be related to hypermethylation of the promoter. Expression of this gene may also be inhibited by binding of a specific MicroRNA to a target sequence in the 3' UTR of the transcripts. A pseudogene of this gene is located on the X chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2011]

VEZT Products (33)

mRNA Protein Name
NM_001352088.2 NP_001339017.1 vezatin isoform a
NM_001352089.2 NP_001339018.1 vezatin isoform c
NM_001352090.2 NP_001339019.1 vezatin isoform d
NM_001352091.2 NP_001339020.1 vezatin isoform e
NM_001352092.2 NP_001339021.1 vezatin isoform f
NM_001352093.2 NP_001339022.1 vezatin isoform f
NM_001352094.2 NP_001339023.1 vezatin isoform g
NM_001352095.2 NP_001339024.1 vezatin isoform g
NM_001352096.2 NP_001339025.1 vezatin isoform g
NM_001352097.2 NP_001339026.1 vezatin isoform h
NM_001352098.2 NP_001339027.1 vezatin isoform i
NM_001352099.2 NP_001339028.1 vezatin isoform j
NM_001352100.2 NP_001339029.1 vezatin isoform k
NM_001352101.2 NP_001339030.1 vezatin isoform l
NM_001352102.2 NP_001339031.1 vezatin isoform l
NM_001352103.2 NP_001339032.1 vezatin isoform m
NM_001352104.2 NP_001339033.1 vezatin isoform m
NM_001352105.2 NP_001339034.1 vezatin isoform m
NM_001352106.2 NP_001339035.1 vezatin isoform m
NM_001352107.2 NP_001339036.1 vezatin isoform m
NM_001352108.2 NP_001339037.1 vezatin isoform n
NM_001352109.2 NP_001339038.1 vezatin isoform o
NM_001352110.2 NP_001339039.1 vezatin isoform v
NM_001352111.2 NP_001339040.1 vezatin isoform p
NM_001352112.2 NP_001339041.1 vezatin isoform q
NM_001352113.2 NP_001339042.1 vezatin isoform r
NM_001352114.2 NP_001339043.1 vezatin isoform s
NM_001352115.2 NP_001339044.1 vezatin isoform t
NM_001352116.2 NP_001339045.1 vezatin isoform t
NM_001352117.2 NP_001339046.1 vezatin isoform t
NM_001352118.2 NP_001339047.1 vezatin isoform w
NM_001352119.2 NP_001339048.1 vezatin isoform u
NM_017599.4 NP_060069.3 vezatin isoform b

VEZT Protein Structure

Vezatin

Vezatin: Mysoin-binding motif of peroxisomes (150 - 440)

  • 0
  • 200
  • 400
  • 600
  • 779 a.a.
Protein Preferred Names Protein Names

vezatin

Related Diseases

Diseases Alias
Anterior Compartment Syndrome
Usher Syndrome, Type Iid

  • Usher Syndrome Type 2d

  • USH2D

  • Usher Syndrome, Type 2d

  • Usher Syndrome Type Iid

  • Usher Syndrome 2d

  • Usher Syndrome, Type Ii
Usher Syndrome, Type I

  • USH1

  • Usher Syndrome Type 1

  • Us1

  • Usher Syndrome, Type 1b

  • Usher Syndrome Type 1e

  • Retinitis Pigmentosa And Congenital Deafness

  • Usher Syndrome, Type Ie

  • USH1E

  • Usher Syndrome, Type 1e

  • Usher Syndrome, Type 1a

  • Usher Syndrome, Type Ib

  • Usher Syndrome Type 1b

  • Usher Syndrome Type Ie

  • Usher Syndrome Type I

  • Usher 1

  • Usher Syndrome, Type 1

  • Ush1a

  • Usher Syndrome, Type I, French Variety

  • Usher Syndrome, Type Ia

  • Usher Syndrome 1b

  • USH1B

  • Usher'S Syndrome Type 1b

  • Usher Syndrome Type Ib

  • Ushib
Gastric Cancer

  • Stomach Cancer

  • Gastric Carcinoma

  • Stomach Carcinoma

  • Gastric Cancer, Somatic

  • Gastric Neoplasm

  • Carcinoma Of Stomach

  • Stomach Neoplasms

  • Malignant Neoplasm Of Stomach

  • Gastric Cancer Risk After H. Pylori Infection

  • Cancer Of The Stomach

  • Adult Stomach Cancer

  • Adult Stomach Carcinoma

  • GASC

  • Gastric Cancer Intestinal

  • Gastric Cancers

  • Gastric Carcinomas

  • Cancer, Gastric

  • Stomach Neoplasm

  • Malignant Neoplasm Of Body Of Stomach

  • Malignant Tumor Of Lesser Curve Of Stomach

  • Gastrocarcinoma Of Unspecified Site

  • Leather Bottle Stomach

  • Carcinoma Of Fundus Of Stomach

  • Cancer Of Fundus Of Stomach

  • Primary Malignant Neoplasm Of Body Of Stomach

  • Cancer Of Body Of Stomach

  • Primary Malignant Neoplasm Of Pyloric Antrum

  • Pyloric Antrum Cancer

  • Malignant Tumour Of Stomach
Deafness, Autosomal Recessive 12

  • DFNB12

  • Deafness, Autosomal Recessive 12, Modifier Of

  • Autosomal Recessive Nonsyndromic Deafness 12

  • Autosomal Recessive Deafness 12

  • Deafness, Autosomal Recessive, 12

  • Congenital Neurosensory Deafness Autosomal Recessive 12

  • Non-Syndromic Neurosensory Deafness Autosomal Recessive Type 12

  • Non-Syndromic Sensorineural Deafness Autosomal Recessive Type 12

  • Deafness, Autosomal Recessive, Type 12
Usher Syndrome Type 2

  • Ush2

  • Usher Syndrome Type Ii
Usher Syndrome

  • Deafness-Retinitis Pigmentosa Syndrome

  • Dystrophia Retinae Pigmentosa-Dysostosis Syndrome

  • Graefe-Usher Syndrome

  • Hallgren Syndrome

  • Usher'S Syndrome

  • Retinitis Pigmentosa-Deafness Syndrome

  • Retinitis Pigmentosa-Hearing Loss Syndrome

  • Ush

  • Usher Syndromes
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15642 VEZT Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus VEZT RGD RGD:1359117
Bos taurus VEZT VGNC VGNC:36789
Felis catus VEZT VGNC VGNC:66940
Mus musculus VEZT MGD MGI:2143698
Macaca mulatta VEZT VGNC VGNC:79120
Canis familiaris VEZT VGNC VGNC:49719
Others VEZT NCBI