2. Gene
  3. VEZT - vezatin, adherens junctions transmembrane protein Gene

VEZT - vezatin, adherens junctions transmembrane protein Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as VEZATIN

Gene ID: 55591 | Gene type: protein coding

About VEZT

Cytogenetic location: 12q22 Genomic coordinates (GRCh38): 12:95,217,807-95,302,799 (from NCBI)

This gene has 40 transcripts (splice variants) and 208 orthologues. Ubiquitous expression in thyroid (RPKM 16.2), placenta (RPKM 10.3) and 25 other tissues.

Summary

This gene encodes a transmembrane protein which has been localized to adherens junctions and shown to bind to Myosin VIIA. Examination of expression of this gene in gastric Cancer tissues have shown that expression is decreased which appears to be related to hypermethylation of the promoter. Expression of this gene may also be inhibited by binding of a specific MicroRNA to a target sequence in the 3' UTR of the transcripts. A pseudogene of this gene is located on the X chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2011]

VEZT Products(33)

mRNA Protein Name
NM_001352088.2 NP_001339017.1 vezatin isoform a
NM_001352089.2 NP_001339018.1 vezatin isoform c
NM_001352090.2 NP_001339019.1 vezatin isoform d
NM_001352091.2 NP_001339020.1 vezatin isoform e
NM_001352092.2 NP_001339021.1 vezatin isoform f
NM_001352093.2 NP_001339022.1 vezatin isoform f
NM_001352094.2 NP_001339023.1 vezatin isoform g
NM_001352095.2 NP_001339024.1 vezatin isoform g
NM_001352096.2 NP_001339025.1 vezatin isoform g
NM_001352097.2 NP_001339026.1 vezatin isoform h
NM_001352098.2 NP_001339027.1 vezatin isoform i
NM_001352099.2 NP_001339028.1 vezatin isoform j
NM_001352100.2 NP_001339029.1 vezatin isoform k
NM_001352101.2 NP_001339030.1 vezatin isoform l
NM_001352102.2 NP_001339031.1 vezatin isoform l
NM_001352103.2 NP_001339032.1 vezatin isoform m
NM_001352104.2 NP_001339033.1 vezatin isoform m
NM_001352105.2 NP_001339034.1 vezatin isoform m
NM_001352106.2 NP_001339035.1 vezatin isoform m
NM_001352107.2 NP_001339036.1 vezatin isoform m
NM_001352108.2 NP_001339037.1 vezatin isoform n
NM_001352109.2 NP_001339038.1 vezatin isoform o
NM_001352110.2 NP_001339039.1 vezatin isoform v
NM_001352111.2 NP_001339040.1 vezatin isoform p
NM_001352112.2 NP_001339041.1 vezatin isoform q
NM_001352113.2 NP_001339042.1 vezatin isoform r
NM_001352114.2 NP_001339043.1 vezatin isoform s
NM_001352115.2 NP_001339044.1 vezatin isoform t
NM_001352116.2 NP_001339045.1 vezatin isoform t
NM_001352117.2 NP_001339046.1 vezatin isoform t
NM_001352118.2 NP_001339047.1 vezatin isoform w
NM_001352119.2 NP_001339048.1 vezatin isoform u
NM_017599.4 NP_060069.3 vezatin isoform b

VEZT Protein Structure

Vezatin

Vezatin: Mysoin-binding motif of peroxisomes (150 - 440)

  • 0
  • 200
  • 400
  • 600
  • 779 a.a.
Protein Preferred Names Protein Names

vezatin

Related Diseases

Diseases Alias
Anterior Compartment Syndrome
Usher Syndrome, Type Iid

Usher Syndrome Type 2d

USH2D

Usher Syndrome, Type 2d

Usher Syndrome Type Iid

Usher Syndrome 2d

Usher Syndrome, Type Ii
Usher Syndrome, Type I

USH1

Usher Syndrome Type 1

Us1

Usher Syndrome, Type 1b

Usher Syndrome Type 1e

Retinitis Pigmentosa And Congenital Deafness

Usher Syndrome, Type Ie

USH1E

Usher Syndrome, Type 1e

Usher Syndrome, Type 1a

Usher Syndrome, Type Ib

Usher Syndrome Type 1b

Usher Syndrome Type Ie

Usher Syndrome Type I

Usher 1

Usher Syndrome, Type 1

Ush1a

Usher Syndrome, Type I, French Variety

Usher Syndrome, Type Ia

Usher Syndrome 1b

USH1B

Usher'S Syndrome Type 1b

Usher Syndrome Type Ib

Ushib
Gastric Cancer

Stomach Cancer

Gastric Carcinoma

Stomach Carcinoma

Gastric Cancer, Somatic

Gastric Neoplasm

Carcinoma Of Stomach

Stomach Neoplasms

Malignant Neoplasm Of Stomach

Gastric Cancer Risk After H. Pylori Infection

Cancer Of The Stomach

Adult Stomach Cancer

Adult Stomach Carcinoma

GASC

Gastric Cancer Intestinal

Gastric Cancers

Gastric Carcinomas

Cancer, Gastric

Stomach Neoplasm

Malignant Neoplasm Of Body Of Stomach

Malignant Tumor Of Lesser Curve Of Stomach

Gastrocarcinoma Of Unspecified Site

Leather Bottle Stomach

Carcinoma Of Fundus Of Stomach

Cancer Of Fundus Of Stomach

Primary Malignant Neoplasm Of Body Of Stomach

Cancer Of Body Of Stomach

Primary Malignant Neoplasm Of Pyloric Antrum

Pyloric Antrum Cancer

Malignant Tumour Of Stomach
Deafness, Autosomal Recessive 12

DFNB12

Deafness, Autosomal Recessive 12, Modifier Of

Autosomal Recessive Nonsyndromic Deafness 12

Autosomal Recessive Deafness 12

Deafness, Autosomal Recessive, 12

Congenital Neurosensory Deafness Autosomal Recessive 12

Non-Syndromic Neurosensory Deafness Autosomal Recessive Type 12

Non-Syndromic Sensorineural Deafness Autosomal Recessive Type 12

Deafness, Autosomal Recessive, Type 12
Usher Syndrome Type 2

Ush2

Usher Syndrome Type Ii
Usher Syndrome

Deafness-Retinitis Pigmentosa Syndrome

Dystrophia Retinae Pigmentosa-Dysostosis Syndrome

Graefe-Usher Syndrome

Hallgren Syndrome

Usher'S Syndrome

Retinitis Pigmentosa-Deafness Syndrome

Retinitis Pigmentosa-Hearing Loss Syndrome

Ush

Usher Syndromes
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15642 VEZT Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus VEZT RGD RGD:1359117
Bos taurus VEZT VGNC VGNC:36789
Felis catus VEZT VGNC VGNC:66940
Mus musculus VEZT MGD MGI:2143698
Macaca mulatta VEZT VGNC VGNC:79120
Canis familiaris VEZT VGNC VGNC:49719