THSD1 - thrombospondin type 1 domain containing 1 Gene

Homo sapiens

Also known as TMTSP; ANIB12; UNQ3010

Gene ID: 55901 | Gene type: protein coding

About THSD1

Cytogenetic location: 13q14.3 Genomic coordinates (GRCh38): 13:52,377,167-52,406,172 (from NCBI)

This gene has 3 transcripts (splice variants), 199 orthologues and is associated with 3 phenotypes. Broad expression in lung (RPKM 7.5), placenta (RPKM 5.7) and 21 other tissues.

Summary

The protein encoded by this gene contains a type 1 thrombospondin domain, which is found in a number of proteins involved in the complement pathway, as well as in extracellular matrix proteins. Alternatively spliced transcript variants encoding different isoforms have been observed for this gene. [provided by RefSeq, Jan 2009]

THSD1 Products(2)

mRNA	Protein	Name
NM_018676.4	NP_061146.1	thrombospondin type-1 domain-containing protein 1 isoform 1 precursor
NM_199263.3	NP_954872.1	thrombospondin type-1 domain-containing protein 1 isoform 2 precursor

THSD1 Protein Structure

TSP_1

0
200
400
600
800
852 a.a.

Protein Preferred Names

Protein Names

thrombospondin type-1 domain-containing protein 1

4833423O18Rik

Recombinant THSD1 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P71360	THSD1 Protein, Human (HEK293, His)	Q9NS62-2 (E25-I361)	≥95%

Related Diseases

Diseases

Alias

Aneurysm, Intracranial Berry, 12

ANIB12

Intracranial Berry Aneurysm 12

Familial Cerebral Saccular Aneurysm

Familial Berry Aneurysm

Familial Intracranial Saccular Aneurysm

Hydrops Fetalis, Nonimmune

Hydrops Fetalis	Non-Immune Hydrops Fetalis
NIHF	Familial Non-Immune Hydrops Fetalis
Hydrops Fetalis Nonimmune	Idiopathic Hydrops Fetalis
Hb Bart'S Hydrops Fetalis	Alpha-Thalassemia Hydrops Fetalis
Alpha-Thalassemia Major	Hemoglobin Bart'S Hydrops Fetalis
Homozygous Alpha0-Thalassemia	Fetal Anasarca
Fetal Hydrops	Generalized Fetal Edema
Hf	Non-Immune Hf
Non-Immune Fetal Edema	Non-Immune Fetal Hydrops
Hydrops Fetalis, Non-Immune	Hemoglobin Bart'S Hydrops Syndrome

Enterokinase Deficiency

Enteropeptidase Deficiency	Congenital Enterokinase Deficiency
Congenital Enteropathy Due To Enteropeptidase Deficiency	Deficiency Of Enteropeptidase
ENTKD

Cerebral Arterial Disease

Cerebral Arterial Diseases

Unilateral Retinoblastoma

Intracranial Berry Aneurysm

Familial Aneurysmal Subarachnoid Hemorrhage	Familial Berry Aneurysm
Familial Intracranial Saccular Aneurysm	Saccular Cerebral Aneurysm
Aneurysm, Intracranial Berry	Aneurysmal Subarachnoid Hemorrhage
Aneurysm, Intracranial Berry, 1

Moyamoya Disease 1

Moyamoya Disease	Spontaneous Occlusion Of The Circle Of Willis
Mymy	Progressive Intracranial Arterial Occlusion
Moyamoya Syndrome	MYMY1
Cerebrovascular Moyamoya Disease	Moya-Moya Disease
Progressive Intracranial Occlusive Arteropathy	Idiopathic Moyamoya Disease

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14503	THSD1 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	THSD1	MGD	MGI:1929096
Rattus norvegicus	THSD1	RGD	RGD:1306998
Canis familiaris	THSD1	VGNC	VGNC:47357
Bos taurus	THSD1	VGNC	VGNC:35849
Felis catus	THSD1	VGNC	VGNC:66175
Macaca mulatta	THSD1	VGNC	VGNC:78402
Others	THSD1	NCBI

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