PLSCR2 - phospholipid scramblase 2 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 57047

Summary

This gene encodes a member of the phospholipid scramblase family. Phospholipid scramblases are membrane proteins that mediate calcium-dependent, non-specific movement of plasma membrane Phospholipids and phosphatidylserine exposure. The encoded protein contains a low affinity calcium binding motif and may play a role in blood coagulation and Apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
Low expression observed in reference dataset.

PLSCR2 Products (7)

mRNA Protein Name
NM_001199978.3 NP_001186907.1 phospholipid scramblase 2 isoform 1
NM_001199979.1 NP_001186908.1 phospholipid scramblase 2 isoform 2
NM_001395437.1 NP_001382366.1 phospholipid scramblase 2 isoform 3
NM_001395438.1 NP_001382367.1 phospholipid scramblase 2 isoform 3
NM_001395439.1 NP_001382368.1 phospholipid scramblase 2 isoform 3
NM_001395440.1 NP_001382369.1 phospholipid scramblase 2 isoform 1
NM_020359.4 NP_065092.1 phospholipid scramblase 2 isoform 3

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PLSCR2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
PLSCR2 Q9NRY7 GNG13 Homo sapiens Q9P2W3
Validated Y2H
32296183
Intra
PLSCR2 Q9NRY7 LCE1A Homo sapiens Q5T7P2
Validated Y2H
32296183
Intra
PLSCR2 Q9NRY7 LYPD1 Homo sapiens Q8N2G4-2
Y2H Prey Pooling
32296183
Intra
PLSCR2 Q9NRY7 LYPD1 Homo sapiens Q8N2G4-2
Y2H Array
32296183
Intra
PLSCR2 Q9NRY7 COQ9 Homo sapiens O75208
Y2H Prey Pooling
32296183
Intra
PLSCR2 Q9NRY7 COQ9 Homo sapiens O75208
Y2H Array
32296183
Intra
PLSCR2 Q9NRY7 BSND Homo sapiens Q8WZ55
Y2H Array
32296183
Intra
PLSCR2 Q9NRY7 BSND Homo sapiens Q8WZ55
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10741 PLSCR1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS10742 PLSCR3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS10743 PLSCR4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18201 Plscr1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24677 Plscr1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown