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57047

" within the MedChemExpress (MCE) catalog. Here are the results you might be looking for.

By Targets:	Calcium Channel (1) COX (1) Histamine Receptor (1) MicroRNA (20) Opioid Receptor (2)
By Research Areas:	Cancer (20) Cardiovascular Disease (1) Endocrinology (1) Inflammation/Immunology (3)
Oligonucleotides:	miRNA mimics (5) miRNA antagomirs (5) miRNA agomirs (5) MicroRNAs (20) miRNA inhibitors (5)

Inhibitors & Agonists

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-14157

ADL-5747	Opioid Receptor	Inflammation/Immunology
ADL-5747 is a selective and orally active agonist of the δ-opioid receptor (DOR). By binding to the δ-opioid receptors, ADL-5747 activates these receptors, thereby playing a role in pain management pathways. ADL-5747 can be used for research into pain management mechanisms .

HY-120816

WU-07047	Calcium Channel	Cardiovascular Disease
WU-07047, a simplified analog of YM-254890 (HY-111557), is a selective Gαq/11 inhibitor. WU-07047 can inhibit nucleotide exchange .

HY-171470

RS-57067	COX	Inflammation/Immunology
RS-57067 is a COX-2 inhibitor with a K_i of 16.9 μM. RS-57067 reduces the production of prostaglandins (such as PGE2) by inhibiting COX-2, thereby alleviating the inflammatory response. RS-57067 can be used in the research of inflammatory and immune diseases .

HY-14157A

*ADL-5747* hydrochloride**	Opioid Receptor	Inflammation/Immunology
ADL-5747 hydrochloride is a selective and orally active agonist of the δ-opioid receptor (DOR). By binding to the δ-opioid receptors, ADL-5747 hydrochloride activates these receptors, thereby playing a role in pain management pathways. ADL-5747 hydrochloride can be used for research into pain management mechanisms .

HY-160979

Bisfentidine DA-5047	Histamine Receptor	Others Endocrinology
Bisfentidine is an H2 receptor antagonist, Bisfentidine can block the H2 receptor on the cells of the stomach wall, and reduce the secretion of stomach acid. Bisfentidine binds to cytochrome P-450 in liver microsomes and affects drug metabolism. Bisfentidine can be used in the study of metabolic processes of drugs, lipid peroxidation processes and peptic ulcers diseases .

HY-R01787

*hsa-miR-5704* mimic**	MicroRNA	Cancer
hsa-miR-5704 mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

hsa-miR-5704 mimic hsa-miR-5704 mimic

HY-R01790

*hsa-miR-5707* mimic**	MicroRNA	Cancer
hsa-miR-5707 mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

hsa-miR-5707 mimic hsa-miR-5707 mimic

HY-R01515

*hsa-miR-5047* mimic**	MicroRNA	Cancer
hsa-miR-5047 mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

hsa-miR-5047 mimic hsa-miR-5047 mimic

HY-R03837

*mmu-miR-7047-5p mimic*	MicroRNA	Cancer
mmu-miR-7047-5p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

mmu-miR-7047-5p mimic mmu-miR-7047-5p mimic

HY-RI03837

*mmu-miR-7047-5p inhibitor*	MicroRNA	Cancer
mmu-miR-7047-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

mmu-miR-7047-5p inhibitor mmu-miR-7047-5p inhibitor

HY-R03836

*mmu-miR-7047-3p mimic*	MicroRNA	Cancer
mmu-miR-7047-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

mmu-miR-7047-3p mimic mmu-miR-7047-3p mimic

HY-R01515A

*hsa-miR-5047* agomir**	MicroRNA	Cancer
hsa-miR-5047 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-5047 agomir hsa-miR-5047 agomir

HY-RI01790A

*hsa-miR-5707* antagomir**	MicroRNA	Cancer
hsa-miR-5707 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-5707 antagomir hsa-miR-5707 antagomir

HY-RI01515

*hsa-miR-5047* inhibitor**	MicroRNA	Cancer
hsa-miR-5047 inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

hsa-miR-5047 inhibitor hsa-miR-5047 inhibitor

HY-R01787A

*hsa-miR-5704* agomir**	MicroRNA	Cancer
hsa-miR-5704 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-5704 agomir hsa-miR-5704 agomir

HY-RI01787

*hsa-miR-5704* inhibitor**	MicroRNA	Cancer
hsa-miR-5704 inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

hsa-miR-5704 inhibitor hsa-miR-5704 inhibitor

HY-R01790A

*hsa-miR-5707* agomir**	MicroRNA	Cancer
hsa-miR-5707 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-5707 agomir hsa-miR-5707 agomir

HY-RI01515A

*hsa-miR-5047* antagomir**	MicroRNA	Cancer
hsa-miR-5047 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-5047 antagomir hsa-miR-5047 antagomir

HY-RI01790

*hsa-miR-5707* inhibitor**	MicroRNA	Cancer
hsa-miR-5707 inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

hsa-miR-5707 inhibitor hsa-miR-5707 inhibitor

HY-RI01787A

*hsa-miR-5704* antagomir**	MicroRNA	Cancer
hsa-miR-5704 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-5704 antagomir hsa-miR-5704 antagomir

HY-R03836A

*mmu-miR-7047-3p agomir*	MicroRNA	Cancer
mmu-miR-7047-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

mmu-miR-7047-3p agomir mmu-miR-7047-3p agomir

HY-RI03837A

*mmu-miR-7047-5p antagomir*	MicroRNA	Cancer
mmu-miR-7047-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

mmu-miR-7047-5p antagomir mmu-miR-7047-5p antagomir

HY-R03837A

*mmu-miR-7047-5p agomir*	MicroRNA	Cancer
mmu-miR-7047-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

mmu-miR-7047-5p agomir mmu-miR-7047-5p agomir

HY-RI03836

*mmu-miR-7047-3p inhibitor*	MicroRNA	Cancer
mmu-miR-7047-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

mmu-miR-7047-3p inhibitor mmu-miR-7047-3p inhibitor

HY-RI03836A

*mmu-miR-7047-3p antagomir*	MicroRNA	Cancer
mmu-miR-7047-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

mmu-miR-7047-3p antagomir mmu-miR-7047-3p antagomir

Host:	Mouse (4)
Reactivity:	Human (4) Rat (1) Mouse (2)
Application:	IHC-P (4) ICC/IF (3) IP (1) WB (1) ELISA (3)
Isotype:	IgG1 (4)
Conjugation:	Non-conjugated (4)
Clonality:	Monoclonal (4)
Modification:	Unmodified (4)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P86012

	TSHB Antibody (YA5704)	IHC-P, ICC/IF, ELISA	Human
	TSHB Antibody (YA5704) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to TSHB.

HY-P86015

	Mast cell tryptase Antibody (YA5707)	IHC-P, ICC/IF, ELISA	Human
	Mast cell tryptase Antibody (YA5707) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Mast cell tryptase.

HY-P87364

	WNT4 Antibody (YA7047) MGC123964 antibody; Protein Wnt-4 antibody; RP23-246F18.1 antibody; SERKAL antibody; Wingless type MMTV integration site family member 4 precursor antibody; WNT 4 antibody; WNT 4 protein precursor antibody; WNT4 antibody; WNT4_HUMAN antibody	WB, IHC-P, ICC/IF, IP	Human, Mouse, Rat
	WNT4 Antibody (YA7047) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to WNT4.

HY-P86055

	P Glycoprotein Antibody (YA5747) ABC20; ABCB1; ATP binding cassette, sub family B; MDR/TAP; , member 1; ATP-binding cassette sub-family B member 1; CD243; CLCS; Colchicin sensitivity; Doxorubicin resistance; GP170; MDR1; MDR1_HUMAN; Multidrug resistance 1; Multidrug resistance protein 1; P glycoprotein 1; P gp; P-glycoprotein 1; PGY1	IHC-P, ELISA	Human, Mouse
	P Glycoprotein Antibody (YA5747) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to P Glycoprotein.

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Cat. No.	Product Name		Classification

HY-R01787

*hsa-miR-5704* mimic**		MicroRNAs miRNA mimics
hsa-miR-5704 mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-R01790

*hsa-miR-5707* mimic**		MicroRNAs miRNA mimics
hsa-miR-5707 mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-R01515

*hsa-miR-5047* mimic**		MicroRNAs miRNA mimics
hsa-miR-5047 mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-R03837

*mmu-miR-7047-5p mimic*		MicroRNAs miRNA mimics
mmu-miR-7047-5p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-RI03837

*mmu-miR-7047-5p inhibitor*		MicroRNAs miRNA inhibitors
mmu-miR-7047-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-R03836

*mmu-miR-7047-3p mimic*		MicroRNAs miRNA mimics
mmu-miR-7047-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-R01515A

*hsa-miR-5047* agomir**		MicroRNAs miRNA agomirs
hsa-miR-5047 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI01790A

*hsa-miR-5707* antagomir**		MicroRNAs miRNA antagomirs
hsa-miR-5707 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI01515

*hsa-miR-5047* inhibitor**		MicroRNAs miRNA inhibitors
hsa-miR-5047 inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-R01787A

*hsa-miR-5704* agomir**		MicroRNAs miRNA agomirs
hsa-miR-5704 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI01787

*hsa-miR-5704* inhibitor**		MicroRNAs miRNA inhibitors
hsa-miR-5704 inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-R01790A

*hsa-miR-5707* agomir**		MicroRNAs miRNA agomirs
hsa-miR-5707 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI01515A

*hsa-miR-5047* antagomir**		MicroRNAs miRNA antagomirs
hsa-miR-5047 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI01790

*hsa-miR-5707* inhibitor**		MicroRNAs miRNA inhibitors
hsa-miR-5707 inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-RI01787A

*hsa-miR-5704* antagomir**		MicroRNAs miRNA antagomirs
hsa-miR-5704 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-R03836A

*mmu-miR-7047-3p agomir*		MicroRNAs miRNA agomirs
mmu-miR-7047-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI03837A

*mmu-miR-7047-5p antagomir*		MicroRNAs miRNA antagomirs
mmu-miR-7047-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-R03837A

*mmu-miR-7047-5p agomir*		MicroRNAs miRNA agomirs
mmu-miR-7047-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI03836

*mmu-miR-7047-3p inhibitor*		MicroRNAs miRNA inhibitors
mmu-miR-7047-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-RI03836A

*mmu-miR-7047-3p antagomir*		MicroRNAs miRNA antagomirs
mmu-miR-7047-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

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