PLAAT1 - phospholipase A and acyltransferase 1 Gene

Homo sapiens

Also known as A-C1; HRSL1; HSD28; HRASLS; HRASLS1; PLA/AT1; PLAAT-1; H-REV107

Gene ID: 57110 | Gene type: protein coding

About PLAAT1

Cytogenetic location: 3q29 Genomic coordinates (GRCh38): 3:193,240,606-193,281,426 (from NCBI)

This gene has 3 transcripts (splice variants), 273 orthologues and 7 paralogues. Biased expression in testis (RPKM 17.3), thyroid (RPKM 1.8) and 3 other tissues.

Summary

Enables Acyltransferase activity, transferring groups other than amino-acyl groups and Phospholipase activity. Involved in N-acylphosphatidylethanolamine metabolic process and phosphatidylcholine metabolic process. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

PLAAT1 Products(2)

mRNA	Protein	Name
NM_001366112.1	NP_001353041.1	phospholipase A and acyltransferase 1
NM_020386.5	NP_065119.3	phospholipase A and acyltransferase 1

PLAAT1 Protein Structure

LRAT

0
100
168 a.a.

Protein Preferred Names

Protein Names

phospholipase A and acyltransferase 1

H-REV107 protein-related protein

Related Diseases

Diseases

Alias

Bothnia Retinal Dystrophy

Vasterbotten Dystrophy	BRD
Dystrophy, Retinal, Bothnia

Poland Syndrome

Poland Anomaly	Poland Sequence
Poland Syndactyly	Poland'S Syndrome
Poland'S Anomaly	Poland'S Syndactyly
Acro-Pectoro-Renal Field Defect	Brachydactyly, Absent Pectoral Muscles And Agenesis/Hypoplasia Of Kidneys
Unilateral Defect Of Pectoralis Muscle And Syndactyly Of The Hand	Unilateral Defect Of Pectoralis Major And Syndactyly Of The Hand

Microphthalmia, Syndromic 9

Matthew-Wood Syndrome	Spear Syndrome
Anophthalmia/Microphthalmia And Pulmonary Hypoplasia	Microphthalmia, Isolated, With Coloboma 8
MCOPS9	Anophthalmia, Clinical, With Mild Facial Dysmorphism And Variable Malformations Of The Lung, Heart, And Diaphragm
Pulmonary Hypoplasia-Diaphragmatic Hernia-Anophthalmia-Cardiac Defect	Pdac
Pulmonary Agenesis, Microphthalmia, And Diaphragmatic Defect	Pmd
Syndromic Microphthalmia 9	Anophthalmia-Pulmonary Hypoplasia Syndrome
Clinical Anophthalmia Mild Facial Dysmorphism Lung Heart And Diaphragm Malformations	Pulmonary Agenesis Microphthalmi And Diaphragmatic Defect
Microphthalmia Syndromic 9	Matthew Wood Syndrome
Pdac Syndrome	Pulmonary Hypoplasia-Diaphragmatic Hernia-Anophthalmia-Cardiac Defect Syndrome
Microphthalmia, Isolated, With Coloboma, 8	MCOPCB8
Isolated Colobomatous Microphthalmia 8	Microphthalmia, Syndromic, 9
Anophthalmia With Pulmonary Hypoplasia	Microphthalmia Syndromic, Type 9
Anophthalmia And Pulmonary Hypoplasia

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10637	PLAAT1 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	PLAAT1	VGNC	VGNC:102805
Bos taurus	PLAAT1	VGNC	VGNC:53580
Macaca mulatta	PLAAT1	VGNC	VGNC:76029
Canis familiaris	PLAAT1	VGNC	VGNC:41782
Rattus norvegicus	PLAAT1	RGD	RGD:1309485
Mus musculus	PLAAT1	MGD	MGI:1351473

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