MYORG - myogenesis regulating glycosidase (putative) Gene

Also Known as IBGC7; NET37; KIAA1161

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 57462

About MYORG

Cytogenetic location: 9p13.3 Genomic coordinates (GRCh38): 9:34,366,666-34,376,898 (from NCBI)

This gene has 2 transcripts (splice variants), 281 orthologues, 6 paralogues and is associated with 2 phenotypes. Broad expression in duodenum (RPKM 7.6), small intestine (RPKM 7.3) and 18 other tissues.

Summary

Predicted to enable hydrolase activity, hydrolyzing O-glycosyl compounds. Involved in skeletal muscle fiber development. Predicted to be located in endoplasmic reticulum membrane and nuclear membrane. Implicated in basal ganglia calcification. [provided by Alliance of Genome Resources, Apr 2022]

MYORG Products (1)

mRNA Protein Name
NM_020702.5 NP_065753.2 myogenesis-regulating glycosidase

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in skeletal muscle fiber development IMP
IMP: Inferred from mutant phenotype
19706595 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

MYORG Protein Structure

Glyco_hydro_31

Glyco_hydro_31: Glycosyl hydrolases family 31 (292 - 674)

  • 0
  • 200
  • 400
  • 600
  • 680 a.a.
Protein Preferred Names Protein Names

myogenesis-regulating glycosidase

Related Diseases

Diseases Alias
Basal Ganglia Calcification, Idiopathic, 7, Autosomal Recessive

  • IBGC7
Basal Ganglia Calcification, Idiopathic, 1

  • Primary Familial Brain Calcification

  • Pfbc

  • Bspdc

  • Bilateral Striopallidodentate Calcinosis

  • Cerebrovascular Ferrocalcinosis

  • IBGC1

  • Familial Idiopathic Basal Ganglia Calcification

  • Idiopathic Basal Ganglia Calcification 1

  • Striopallidodentate Calcinosis, Bilateral

  • Striopallidodentate Calcinosis, Autosomal Dominant, Adult-Onset

  • Cerebral Calcification, Nonarteriosclerotic, Idiopathic, Adult-Onset

  • Ferrocalcinosis, Cerebrovascular

  • Fahr Disease, Familial, Formerly

  • Basal Ganglia Calcification, Idiopathic, 3, Formerly

  • Ibgc3, Formerly

  • Basal Ganglia Calcification, Idiopathic, 2, Formerly

  • Ibgc2, Formerly

  • Fibgc

  • Striopallidodentate Calcinosis

  • Idiopathic Basal Ganglia Calcification

  • Ferrocalcinosis Cerebro Vascular

  • Autosomal Dominant Adult-Onset Striopallidodentate Calcinosis

  • Familial Fahr Disease

  • Ibgc2

  • Ibgc3

  • Idiopathic Basal Ganglia Calcification 2

  • Idiopathic Basal Ganglia Calcification 3

  • Non-Arteriosclerotic, Idiopathic, Adult-Onset Cerebral Calcification

  • Basal Ganglia Calcification, Idiopathic

  • Calcification, Basal Ganglia, Idiopathic

  • Calcification, Basal Ganglia, Idiopathic, Type 1

  • Fahr'S Syndrome
Basal Ganglia Calcification

  • Fahr'S Syndrome

  • Fahr'S Disease

  • Fahr Disease
Basal Ganglia Disease

  • Basal Ganglia Diseases

  • Basal Ganglia Disorders

  • Abnormality Of The Basal Ganglia
Optic Disk Drusen

  • Optic Disc Drusen

  • Drusen Of Optic Disc

  • Optic Nerve Head Drusen

  • Drusen Optic Disc
Parkinsonism

  • Parkinsonism-Plus

  • Idiopathic Parkinsonism

  • Primary Parkinsonism

  • Paralysis Agitans Syndrome

  • Parkinsonian Syndrome

  • Trembling Paralysis

  • Paralysis Agitans

  • Shaking Palsy

  • Shaking Paralysis
Lingual-Facial-Buccal Dyskinesia

  • Orofacial Dyskinesia

  • Oro-Facial Dyskinesia

  • Dyskinesias
Dystonia

  • Dystonic Disease

  • Dystonic Disorder

  • Dystonia Disorders

  • Neuroleptic Dyskinesia
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08963 MYORG Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris MYORG VGNC VGNC:55157
Mus musculus MYORG MGD MGI:2140300
Felis catus MYORG VGNC VGNC:102953
Rattus norvegicus MYORG RGD RGD:1309821
Macaca mulatta MYORG VGNC VGNC:103279
Others MYORG NCBI