ZDBF2 - zinc finger DBF-type containing 2 Gene

Also Known as Slx9

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 57683

About ZDBF2

Cytogenetic location: 2q33.3 Genomic coordinates (GRCh38): 2:206,274,663-206,314,427 (from NCBI)

This gene has 10 transcripts (splice variants), 1 gene allele and 93 orthologues. Ubiquitous expression in adrenal (RPKM 4.6), brain (RPKM 4.3) and 25 other tissues.

Summary

This gene encodes a protein containing DBF4-type zinc finger domains. This gene is imprinted and paternally expressed in lymphocytes but is more stochastically expressed in the placenta. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2015]

ZDBF2 Products (3)

mRNA	Protein	Name
NM_001285549.2	NP_001272478.1	DBF4-type zinc finger-containing protein 2 isoform 2
NM_001369654.1	NP_001356583.1	DBF4-type zinc finger-containing protein 2 isoform 1
NM_020923.3	NP_065974.1	DBF4-type zinc finger-containing protein 2 isoform 1

ZDBF2 Protein Structure

zf-DBF

0
400
800
1200
1600
2000
2354 a.a.

Protein Preferred Names	Protein Names
DBF4-type zinc finger-containing protein 2

Related Diseases

Diseases	Alias
Nasopalpebral Lipoma-Coloboma Syndrome	Nasopalpebral Lipoma Coloboma Syndrome NPLCS Palpebral Coloboma-Lipoma Syndrome Palpebral Coloboma Lipoma Syndrome
Achromatopsia 7	ACHM7 Achromatopsia, Type 7
Temple Syndrome	Uniparental Disomy, Maternal, Chromosome 14 Temple Syndrome Due To Paternal 14q32.2 Microdeletion Paternal Del(14)(Q32.2) Temple Syndrome Due To Paternal 14q32.2 Hypomethylation Temple Syndrome Due To Maternal Uniparental Disomy Of Chromosome 14 Upd(14)Mat
Chromosome 2q37 Deletion Syndrome	Albright Hereditary Osteodystrophy-Like Syndrome 2q37 Microdeletion Syndrome Brachydactyly-Intellectual Disability Syndrome Deletion 2q37 2q37 Deletion Syndrome Brachydactyly-Mental Retardation Syndrome Bdmr Albright Hereditary Osteodystrophy Type 3 Del(2)(Q37) Monosomy 2q37qter Albright'S Hereditary Osteodystrophy-Like Syndrome Monosomy 2q37 Chromosome Deletion Syndrome 2q37
Pseudohypoparathyroidism, Type Ib	Pseudohypoparathyroidism Type 1b PHP1B Pseudohypoparathyroidism Ib Pseudohypoparathyroidism Type Ib Php Ib Pseudohypoparathyroidism 1b
Silver-Russell Syndrome 1	Silver-Russell Syndrome Russell-Silver Syndrome Silver-Russell Dwarfism Rss SRS1 Srs Silver Russell Dwarfism Russell Silver Syndrome Silver Russell Syndrome
Transient Neonatal Diabetes Mellitus	Diabetes Mellitus, Transient Neonatal Tndm Chromosome 6-Associated Transient Diabetes Mellitus Dmtn Diabetes Mellitus, 6q24-Related Transient Neonatal Tndm1 Neonatal Diabetes Mellitus, Transient Tndm -[Transient Neonatal Diabetes Mellitus]
Kagami-Ogata Syndrome	Paternal Uniparental Disomy Of Chromosome 14 Uniparental Disomy, Paternal, Chromosome 14 Kos Mca Due To 14q32.2 Maternally Expressed Gene Defect Paternal Uniparental Disomy 14 Kagami-Ogata Syndrome Due To Maternal 14q32.2 Microdeletion Maternal Del(14)(Q32.2) Maternal Monosomy 14q32.2 Kagami-Ogata Syndrome Due To Maternal 14q32.2 Hypermethylation Kagami-Ogata Syndrome Due To Paternal Uniparental Disomy Of Chromosome 14 Upd(14)Pat
Beckwith-Wiedemann Syndrome	Wiedemann-Beckwith Syndrome BWS Exomphalos-Macroglossia-Gigantism Syndrome Emg Syndrome Beckwith-Wiedemann Syndrome Due To Cdkn1c Mutation Emg Abnormality Wbs Exomphalos Macroglossia Gigantism Syndrome Beckwith-Wiedemann Syndrome Due To Nsd1 Mutation Macroglossia Exomphalos Gigantism

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS16010	ZDBF2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	ZDBF2	VGNC	VGNC:99423
Bos taurus	ZDBF2	VGNC	VGNC:56156
Mus musculus	ZDBF2	MGD	MGI:1921134
Felis catus	ZDBF2	VGNC	VGNC:107692
Canis familiaris	ZDBF2	VGNC	VGNC:48576
Rattus norvegicus	ZDBF2	RGD	RGD:1560005
Others	ZDBF2	NCBI