Kcnk1 - potassium two pore domain channel subfamily K member 1 Gene

Also Known as Twik

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 59324

Summary

Enables potassium ion leak channel activity. Involved in potassium ion transmembrane transport and response to nicotine. Located in apical plasma membrane; brush border membrane; and cytoplasm. Is integral component of plasma membrane. Orthologous to human KCNK1 (potassium two pore domain channel subfamily K member 1). [provided by Alliance of Genome Resources, Apr 2022]

Kcnk1 Products (1)

mRNA Protein Name
NM_021688.3 NP_067720.1 potassium channel subfamily K member 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables potassium ion leak channel activity IDA
IDA: Inferred from direct assay
19571146 RGD
Biological Process GO Annotation Evidence References Source
involved in potassium ion transmembrane transport IDA
IDA: Inferred from direct assay
19571146 RGD
involved in response to nicotine IEP
IEP: Inferred from expression pattern
11478936 RGD
Cellular Component GO Annotation Evidence References Source
located in apical plasma membrane IDA
IDA: Inferred from direct assay
12855359 RGD
located in brush border membrane IDA
IDA: Inferred from direct assay
9843722 RGD
located in plasma membrane IMP
IMP: Inferred from mutant phenotype
19571146 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

potassium channel subfamily K member 1

  • inward rectifying potassium channel protein TWIK-1

  • potassium channel K2P1

  • potassium channel, subfamily K, member 1

  • potassium channel, two pore domain subfamily K, member 1

  • putative potassium channel TWIK

  • rTWIK

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07152 KCNK1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21612 Kcnk1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28130 Kcnk1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kcnk1 NCBI NCBI:3775