Hif3a - hypoxia inducible factor 3 subunit alpha Gene

Also Known as Ipas; Mop7

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 64345

Summary

Enables DNA-binding transcription factor activity. Involved in positive regulation of transcription by RNA polymerase II. Located in cytoplasm and nucleus. Biomarker of pulmonary hypertension. Orthologous to human HIF3A (hypoxia inducible factor 3 subunit alpha). [provided by Alliance of Genome Resources, Apr 2022]

Hif3a Products (2)

mRNA Protein Name
NM_001388512.1 NP_001375441.1 hypoxia-inducible factor 3-alpha isoform 2
NM_022528.3 NP_071973.2 hypoxia-inducible factor 3-alpha isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables DNA-binding transcription factor activity IDA
IDA: Inferred from direct assay
11237857 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
21546903 RGD
Biological Process GO Annotation Evidence References Source
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
11237857 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

hypoxia-inducible factor 3-alpha

  • HIF-3-alpha

  • HIF3-alpha

  • HIF3-alpha-1

  • Inhibitory PAS (Per/Arnt/Sim) domain protein

  • hypoxia inducible factor 3, alpha subunit

  • hypoxia inducible factor 3a

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06170 HIF3A Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hif3a NCBI NCBI:64344