2. Gene
  3. Plpp1 - phospholipid phosphatase 1 Gene

Plpp1 - phospholipid phosphatase 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Ppap2a

Gene ID: 64369 | Gene type: protein coding

About Plpp1

Summary

Enables diacylglycerol diphosphate Phosphatase activity; lipid Phosphatase activity; and phosphatidate Phosphatase activity. Involved in phospholipid dephosphorylation; phospholipid metabolic process; and sphingolipid metabolic process. Is integral component of plasma membrane. Orthologous to human PLPP1 (phospholipid Phosphatase 1). [provided by Alliance of Genome Resources, Apr 2022]

Plpp1 Products(1)

mRNA Protein Name
NM_022538.2 NP_071983.2 phospholipid phosphatase 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables ceramide-1-phosphate phosphatase activity IDA
IDA: Inferred from direct assay
10359651 RGD
enables diacylglycerol diphosphate phosphatase activity IDA
IDA: Inferred from direct assay
8663293 RGD
enables phosphatidate phosphatase activity IDA
IDA: Inferred from direct assay
8663293 RGD
enables sphingosine-1-phosphate phosphatase activity IDA
IDA: Inferred from direct assay
8663293 RGD
Biological Process GO Annotation Evidence Reference Source
involved in ceramide metabolic process IDA
IDA: Inferred from direct assay
8663293 RGD
involved in phospholipid dephosphorylation IDA
IDA: Inferred from direct assay
8663293 RGD
involved in phospholipid metabolic process IDA
IDA: Inferred from direct assay
10359651 RGD
involved in sphingosine metabolic process IDA
IDA: Inferred from direct assay
8663293 RGD
Cellular Component GO Annotation Evidence Reference Source
located in plasma membrane IDA
IDA: Inferred from direct assay
8663293 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

phospholipid phosphatase 1

PAP-2a

PAP2-alpha

PAP2a

lipid phosphate phosphohydrolase 1

phosphatidate phosphohydrolase type 2a

phosphatidic acid phosphatase 2a

phosphatidic acid phosphatase type 2A

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10734 PLPP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Plpp1 NCBI NCBI:8611