Ndrg4 - NDRG family member 4 Gene

Also Known as Bdm1; Ndr4; smap8

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 64457

Summary

Involved in brain development; positive regulation of ERK1 and ERK2 cascade; and positive regulation of neuron projection development. Located in endoplasmic reticulum membrane and mitochondrion. Orthologous to human NDRG4 (NDRG family member 4). [provided by Alliance of Genome Resources, Apr 2022]

Ndrg4 Products (6)

mRNA Protein Name
NM_001271091.1 NP_001258020.1 protein NDRG4 isoform 1 precursor
NM_001271092.1 NP_001258021.1 protein NDRG4 isoform 2 precursor
NM_001271093.1 NP_001258022.1 protein NDRG4 isoform 3
NM_001271094.1 NP_001258023.1 protein NDRG4 isoform 4
NM_001271095.1 NP_001258024.1 protein NDRG4 isoform 6
NM_031967.2 NP_114173.2 protein NDRG4 isoform 5

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in positive regulation of ERK1 and ERK2 cascade IDA
IDA: Inferred from direct assay
16408304 RGD
involved in positive regulation of neuron projection development IMP
IMP: Inferred from mutant phenotype
11978393 RGD
Cellular Component GO Annotation Evidence References Source
located in endoplasmic reticulum membrane IDA
IDA: Inferred from direct assay
11978392 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein NDRG4

  • N-myc downstream regulated 4

  • N-myc downstream regulated gene 4

  • brain development-related molecule 1

  • development-related protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09117 NDRG4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22674 Ndrg4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ndrg4 NCBI NCBI:65009