Chrna10 - cholinergic receptor nicotinic alpha 10 subunit Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 64574

Summary

Enables transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential. Involved in negative regulation of ERK1 and ERK2 cascade. Located in axon and perikaryon. Is active in cholinergic synapse. Is integral component of postsynaptic specialization membrane. Orthologous to human CHRNA10 (cholinergic receptor nicotinic alpha 10 subunit). [provided by Alliance of Genome Resources, Apr 2022]

Chrna10 Products (1)

mRNA Protein Name
NM_022639.1 NP_072161.1 neuronal acetylcholine receptor subunit alpha-10 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential IDA
IDA: Inferred from direct assay
11248107 RGD
enables transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential IMP
IMP: Inferred from mutant phenotype
11248107 RGD
Biological Process GO Annotation Evidence References Source
involved in negative regulation of ERK1 and ERK2 cascade IMP
IMP: Inferred from mutant phenotype
20505147 RGD
Cellular Component GO Annotation Evidence References Source
located in axon IDA
IDA: Inferred from direct assay
12401316 RGD
is active in cholinergic synapse IDA
IDA: Inferred from direct assay
11248107 RGD
is active in cholinergic synapse IMP
IMP: Inferred from mutant phenotype
11248107 RGD
located in perikaryon IDA
IDA: Inferred from direct assay
12401316 RGD
is active in postsynaptic specialization membrane IDA
IDA: Inferred from direct assay
18420419 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

neuronal acetylcholine receptor subunit alpha-10

  • NACHR alpha-10

  • cholinergic receptor, nicotinic, alpha 10 (neuronal)

  • cholinergic receptor, nicotinic, alpha polypeptide 10

  • neuronal nicotinic acetylcholine receptor subunit

  • nicotinic acetylcholine receptor subunit alpha-10

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02666 CHRNA10 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Chrna10 NCBI NCBI:57053