HAND2 - Hand2 heart and neural crest derivatives expressed 2 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 64637

Summary

Enables DNA-binding transcription factor activity, RNA polymerase II-specific and DNA-binding transcription factor binding activity. Involved in cellular response to organic cyclic compound; cellular response to retinoic acid; and heart development. Located in nucleus. Orthologous to human HAND2 (heart and neural crest derivatives expressed 2). [provided by Alliance of Genome Resources, Apr 2022]

HAND2 Products (1)

mRNA Protein Name
NM_022696.2 NP_073187.1 heart- and neural crest derivatives-expressed protein 2

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables DNA-binding transcription factor activity, RNA polymerase II-specific IMP
IMP: Inferred from mutant phenotype
11994297 RGD
enables RNA polymerase II-specific DNA-binding transcription factor binding IPI
IPI: Inferred from physical interaction
11994297 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
15486975 RGD
enables transcription coactivator binding IPI
IPI: Inferred from physical interaction
11994297 RGD
Biological Process GO Annotation Evidence References Source
involved in cellular response to organic cyclic compound IEP
IEP: Inferred from expression pattern
11073966 RGD
involved in cellular response to retinoic acid IEP
IEP: Inferred from expression pattern
16619265 RGD
involved in heart development IEP
IEP: Inferred from expression pattern
15486975 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

heart- and neural crest derivatives-expressed protein 2

  • dHand protein

  • deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2

  • heart and neural crest derivatives expressed transcript 2

  • heart- and neural crest derivatives-expressed protein 2-like

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-177787A 2'-Deoxy-N-methyl-AMP ammonium / Unkown
HY-RS05997 HAND2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174480 Mouse Hand2 mRNA / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens HAND2 NCBI NCBI:9464