Scube1 - signal peptide, CUB domain, EGF-like 1 Gene

Also Known as 7330410C13Rik; A630023E24Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 64706

Summary

Predicted to enable identical protein binding activity. Acts upstream of or within positive regulation of smoothened signaling pathway. Predicted to be located in external side of plasma membrane. Predicted to be active in cell surface and extracellular space. Is expressed in several structures, including allantois; embryo ectoderm; embryo mesenchyme; forelimb bud; and genitourinary system. Orthologous to human SCUBE1 (signal peptide, CUB domain and EGF like domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]

Scube1 Products (3)

mRNA Protein Name
NM_001271472.1 NP_001258401.1 signal peptide, CUB and EGF-like domain-containing protein 1 isoform a precursor
NM_001271473.1 NP_001258402.1 signal peptide, CUB and EGF-like domain-containing protein 1 isoform c precursor
NM_022723.3 NP_073560.2 signal peptide, CUB and EGF-like domain-containing protein 1 isoform b precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within positive regulation of smoothened signaling pathway IDA
IDA: Inferred from direct assay
25639508 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

signal peptide, CUB and EGF-like domain-containing protein 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12571 SCUBE1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Scube1 NCBI NCBI:80274