Svep1 - sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 Gene

Also Known as Polydom; 1110021D17Rik; 4833413O10Rik; D430029O09Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 64817

Summary

Enables chromatin binding activity. Acts upstream of or within several processes, including Tie signaling pathway; lymph circulation; and lymph vessel morphogenesis. Located in extracellular space. Is expressed in several structures, including alimentary system; forelimb bud; genitourinary system; spleen; and turbinate bone primordium. Orthologous to human SVEP1 (sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]

Svep1 Products (1)

mRNA Protein Name
NM_022814.2 NP_073725.2 sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables chromatin binding IDA
IDA: Inferred from direct assay
15522233 MGI
enables integrin binding IMP
IMP: Inferred from mutant phenotype
28179430 MGI
enables integrin binding involved in cell-matrix adhesion IDA
IDA: Inferred from direct assay
22654117 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
28179430 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within Tie signaling pathway IMP
IMP: Inferred from mutant phenotype
28179430 MGI
acts upstream of or within epidermis development IMP
IMP: Inferred from mutant phenotype
27892606 MGI
acts upstream of or within gene expression IMP
IMP: Inferred from mutant phenotype
28179430 MGI
acts upstream of or within lymph circulation IMP
IMP: Inferred from mutant phenotype
28179430 MGI
acts upstream of or within lymph vessel development IMP
IMP: Inferred from mutant phenotype
28179432 MGI
acts upstream of or within lymph vessel morphogenesis IMP
IMP: Inferred from mutant phenotype
28179430 MGI
involved in positive regulation of platelet activation IMP
IMP: Inferred from mutant phenotype
36792666 MGI
acts upstream of or within tight junction organization IMP
IMP: Inferred from mutant phenotype
28179432 MGI
Cellular Component GO Annotation Evidence References Source
located in extracellular region IDA
IDA: Inferred from direct assay
22654117 MGI
located in extracellular space IDA
IDA: Inferred from direct assay
28179430 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1

  • polydomain protein (Polydom)

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14058 SVEP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21775 Svep1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28292 Svep1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Svep1 NCBI NCBI:79987