2. Gene
  3. HTR7 - 5-hydroxytryptamine receptor 7 Gene

HTR7 - 5-hydroxytryptamine receptor 7 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as 5Ht7

Gene ID: 65032 | Gene type: protein coding

About HTR7

Primary_assembly 1: 233,636,452-233,760,626 reverse strand.mRatBN7.2:CM026974.1

This gene has 6 transcripts (splice variants), 221 orthologues, 8 paralogues and is associated with 24 phenotypes. Biased expression in Brain (RPKM 28.7), Spleen (RPKM 13.2) and 8 other tissues.

Summary

Enables G protein-coupled serotonin receptor activity and neurotransmitter receptor activity. Involved in several processes, including adenylate cyclase-activating serotonin receptor signaling pathway; detection of mechanical stimulus involved in sensory perception of pain; and modulation of chemical synaptic transmission. Located in several cellular components, including neuronal cell body; rough endoplasmic reticulum; and synaptic vesicle. Is integral component of postsynaptic membrane and integral component of presynaptic membrane. Used to study amnestic disorder; anxiety disorder; childhood absence epilepsy; cognitive disorder; and migraine. Biomarker of irritable bowel syndrome. Human ortholog(s) of this gene implicated in alcohol use disorder. Orthologous to human HTR7 (5-hydroxytryptamine receptor 7). [provided by Alliance of Genome Resources, Apr 2022]

HTR7 Products(1)

mRNA Protein Name
NM_022938.2 NP_075227.1 5-hydroxytryptamine receptor 7

HTR7 Protein Structure

7tmA_5-HT7

7tmA_5-HT7: cd15329 (99 - 397)

7tmA_5-HT7

7tmA_5-HT7: cd15329 (118 - 144)

7tmA_5-HT7

7tmA_5-HT7: cd15329 (157 - 187)

7tmA_5-HT7

7tmA_5-HT7: cd15329 (199 - 221)

7tmA_5-HT7

7tmA_5-HT7: cd15329 (238 - 267)

7tmA_5-HT7

7tmA_5-HT7: cd15329 (322 - 352)

7tmA_5-HT7

7tmA_5-HT7: cd15329 (365 - 390)

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  • 508 a.a.
Protein Preferred Names Protein Names

5-hydroxytryptamine receptor 7

5-HT-7

5-HT-X

5-HT7

5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled

GPRFO

high affinity serotonin receptor (5HT7)

serotonin receptor 7

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06483 HTR7 Human Pre-designed siRNA Set A / Unkown
HY-RS06484 Htr7 Mouse Pre-designed siRNA Set A / Unkown
HY-RS06485 HTR7 Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens HTR7 NCBI NCBI:3363