Fat2 - FAT atypical cadherin 2 Gene

Also Known as Fath2

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 65048

Summary

Predicted to enable calcium ion binding activity. Involved in homophilic cell adhesion via plasma membrane adhesion molecules. Predicted to be located in Golgi apparatus and plasma membrane. Predicted to be integral component of membrane. Predicted to be active in adherens junction. Human ortholog(s) of this gene implicated in spinocerebellar ataxia 45. Orthologous to human FAT2 (FAT atypical Cadherin 2). [provided by Alliance of Genome Resources, Apr 2022]

Fat2 Products (1)

mRNA Protein Name
NM_022954.1 NP_075243.1 protocadherin Fat 2 precursor
Biological Process GO Annotation Evidence References Source
involved in homophilic cell adhesion via plasma membrane adhesion molecules IDA
IDA: Inferred from direct assay
12213440 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protocadherin Fat 2

  • FAT tumor suppressor homolog 2

  • MEGF1

  • multiple EGF-like domains protein 1

  • multiple epidermal growth factor-like domains 1

  • multiple epidermal growth factor-like domains protein 1

Orthologs Information

Species Symbol Source ID
Homo sapiens Fat2 NCBI NCBI:2196