Pyruvic acid-13C
Based on 1 Customer Validation
Pyruvic acid-13C (Acetylformic acid-13C) is the 13C-labeled Pyruvic acid (HY-Y0781). Pyruvic acid is an intermediate metabolite in the metabolism of carbohydrates, proteins, and fats.
For research use only. We do not sell to patients.
- Purity : 96.59%
- CAS No.: 99124-30-8
- Formula: C213CH4O3
- Molecular Weight:89.05
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Storage:Pure form -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Endogenous Metabolite Isoforms
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Biological Activity
Description
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 99124-30-8
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Unlabeled CAS 127-17-3
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Appearance Liquid (Density: 1.281 g/cm3)
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Molecular Weight 89.05
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Formula C213CH4O3
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Color Colorless to light yellow
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SMILES
O[13C](C(C)=O)=O
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Synonyms
Acetylformic acid-13C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (1122.96 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
Purity & Documentation
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Data Sheet (276 KB)
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SDS (477 KB)
- English - EN (477 KB)
- Français - FR (477 KB)
- Deutsch - DE (477 KB)
- Norwegian - NO (477 KB)
- Español - ES (477 KB)
- Swedish - SV (477 KB)
- Italian - IT (477 KB)
- Korean - KR (477 KB)
- Portuguese - PT (477 KB)
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Handling Instructions (2659 KB)
References
[1]. Kładna A, et al. Reactivity of pyruvic acid and its derivatives towards reactive oxygen species. Luminescence. 2015 Nov;30(7):1153-8. [Content Brief]
[3]. Tanaka KI, et al., Pyruvic acid prevents Cu2+/Zn2+-induced neurotoxicity by suppressing mitochondrial injury. Biochem Biophys Res Commun. 2018 Jan 1;495(1):1335-1341. [Content Brief]
[4]. Mazzio EA, et al., Cytoprotection of pyruvic acid and reduced beta-nicotinamide adenine dinucleotide against hydrogen peroxide toxicity in neuroblastoma cells. Neurochem Res. 2003 May;28(5):733-41. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 11.2296 mL | 56.1482 mL | 112.2965 mL | 280.7411 mL |
| 5 mM | 2.2459 mL | 11.2296 mL | 22.4593 mL | 56.1482 mL | |
| 10 mM | 1.1230 mL | 5.6148 mL | 11.2296 mL | 28.0741 mL | |
| 15 mM | 0.7486 mL | 3.7432 mL | 7.4864 mL | 18.7161 mL | |
| 20 mM | 0.5615 mL | 2.8074 mL | 5.6148 mL | 14.0371 mL | |
| 25 mM | 0.4492 mL | 2.2459 mL | 4.4919 mL | 11.2296 mL | |
| 30 mM | 0.3743 mL | 1.8716 mL | 3.7432 mL | 9.3580 mL | |
| 40 mM | 0.2807 mL | 1.4037 mL | 2.8074 mL | 7.0185 mL | |
| 50 mM | 0.2246 mL | 1.1230 mL | 2.2459 mL | 5.6148 mL | |
| 60 mM | 0.1872 mL | 0.9358 mL | 1.8716 mL | 4.6790 mL | |
| 80 mM | 0.1404 mL | 0.7019 mL | 1.4037 mL | 3.5093 mL | |
| 100 mM | 0.1123 mL | 0.5615 mL | 1.1230 mL | 2.8074 mL |
Pyruvic acid-13C Related Classifications
HY-Y0781S1 Related Classifications
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