Pyruvic acid-13C sodium
Based on 1 Customer Validation
Pyruvic acid-13C (sodium) is the 13C-labeled Pyruvic acid. Pyruvic acid is an intermediate metabolite in the metabolism of carbohydrates, proteins, and fats.
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- Pureté : 99.18%
- CAS No.: 87976-70-3
- Formule: C213CH3NaO3
- Masse moléculaire:111.04
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Stockage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
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Activité biologique
Description
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 87976-70-3
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Unlabeled CAS 113-24-6
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Appearance Solid
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Masse moléculaire 111.04
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Formule C213CH3NaO3
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Color White to off-white
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SMILES
O=C(O[Na])[13C](C)=O
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Synonyms
Acetylformic acid-13C sodium
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvant et solubilité
In Vitro:
H2O : 100 mg/mL (900.58 mM; Need ultrasonic)
DMSO : ≥ 50 mg/mL (450.29 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (273 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Instruction de manipulation (2659 KB)
Références
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Kładna A, et al. Reactivity of pyruvic acid and its derivatives towards reactive oxygen species. Luminescence. 2015 Nov;30(7):1153-8. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO / H2O | 1 mM | 9.0058 mL | 45.0288 mL | 90.0576 mL | 225.1441 mL |
| 5 mM | 1.8012 mL | 9.0058 mL | 18.0115 mL | 45.0288 mL | |
| 10 mM | 0.9006 mL | 4.5029 mL | 9.0058 mL | 22.5144 mL | |
| 15 mM | 0.6004 mL | 3.0019 mL | 6.0038 mL | 15.0096 mL | |
| 20 mM | 0.4503 mL | 2.2514 mL | 4.5029 mL | 11.2572 mL | |
| 25 mM | 0.3602 mL | 1.8012 mL | 3.6023 mL | 9.0058 mL | |
| 30 mM | 0.3002 mL | 1.5010 mL | 3.0019 mL | 7.5048 mL | |
| 40 mM | 0.2251 mL | 1.1257 mL | 2.2514 mL | 5.6286 mL | |
| 50 mM | 0.1801 mL | 0.9006 mL | 1.8012 mL | 4.5029 mL | |
| 60 mM | 0.1501 mL | 0.7505 mL | 1.5010 mL | 3.7524 mL | |
| 80 mM | 0.1126 mL | 0.5629 mL | 1.1257 mL | 2.8143 mL | |
| 100 mM | 0.0901 mL | 0.4503 mL | 0.9006 mL | 2.2514 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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