SLC7A4 - solute carrier family 7 member 4 Gene

Also Known as VH; CAT4; CAT-4; HCAT3

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 6545

About SLC7A4

Cytogenetic location: 22q11.21 Genomic coordinates (GRCh38): 22:21,028,718-21,032,561 (from NCBI)

This gene has 3 transcripts (splice variants), 265 orthologues and 12 paralogues. Biased expression in testis (RPKM 11.6), esophagus (RPKM 3.0) and 12 other tissues.

Summary

Predicted to enable amino acid transmembrane transporter activity. Predicted to be involved in amino acid transport. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

SLC7A4 Products (1)

mRNA Protein Name
NM_004173.3 NP_004164.2 cationic amino acid transporter 4

SLC7A4 Protein Structure

AA_permease_2

AA_permease_2: Amino acid permease (37 - 419)

AA_permease_C

AA_permease_C: C-terminus of AA_permease (540 - 590)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 600
  • 635 a.a.
Protein Preferred Names Protein Names

cationic amino acid transporter 4

  • Ig heavy chain variable region

Related Diseases

Diseases Alias
Velocardiofacial Syndrome

  • Shprintzen Syndrome

  • VCFS

  • Chromosome 22q11.2 Deletion Syndrome

  • Vcf Syndrome

  • Shprintzen Vcf Syndrome

  • Vcf-Velocardiofacial Syndrome

  • Velo-Cardio-Facial Syndrome

  • Digeorge Syndrome

  • 22q11 Deletion Syndrome

  • Conotruncal Anomaly Face Syndrome
Rubeosis Iridis
Breast Apocrine Carcinoma

  • Apocrine Carcinoma Of Breast

  • Apocrine Breast Carcinoma
Chromophobe Adenoma

  • Adenoma, Chromophobe

  • Chromophobe Adenoma Of The Pituitary Gland

  • Adenoma Chromophobe
Heparin Cofactor Ii Deficiency

  • Thrombophilia Due To Heparin Cofactor Ii Deficiency

  • THPH10

  • Hcf Ii Deficiency

  • Hcf2 Deficiency

  • Thrombophilia 10 Due To Heparin Cofactor Ii Deficiency

  • Hcf 2 Deficiency

  • Thrombophilia Due To Heparin Cofactor 2 Deficiency

  • Thrombophilia, Due To Heparin Cofactor Ii Deficiency
Vestibular Nystagmus

  • Nystagmus Associated With Disorder Of The Vestibular System
Spondylolysis

  • Acquired Spondylolysis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13330 SLC7A4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta SLC7A4 VGNC VGNC:108056
Felis catus SLC7A4 VGNC VGNC:65426
Rattus norvegicus SLC7A4 RGD RGD:1305905
Bos taurus SLC7A4 VGNC VGNC:34930
Mus musculus SLC7A4 MGD MGI:2146512
Canis familiaris SLC7A4 VGNC VGNC:46475