SLC9A2 - solute carrier family 9 member A2 Gene

Also Known as NHE2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 6549

About SLC9A2

Cytogenetic location: 2q12.1 Genomic coordinates (GRCh38): 2:102,619,553-102,711,355 (from NCBI)

This gene has 3 transcripts (splice variants), 233 orthologues and 10 paralogues. Biased expression in stomach (RPKM 13.9), colon (RPKM 13.0) and 10 other tissues.

Summary

This gene encodes a member of the sodium-hydrogen exchanger (NHE) protein family. These proteins are involved in sodium-ion transport by exchanging intracellular hydrogen ions to external sodium ions and help in the regulation of cell pH and volume. The encoded protein is localized to the apical membrane and is involved in apical absorption of sodium. [provided by RefSeq, Jun 2016]

SLC9A2 Products (1)

mRNA Protein Name
NM_003048.6 NP_003039.2 sodium/hydrogen exchanger 2 precursor

SLC9A2 Protein Structure

Na_H_Exchanger

Na_H_Exchanger: Sodium/hydrogen exchanger family (84 - 484)

  • 0
  • 200
  • 400
  • 600
  • 812 a.a.
Protein Preferred Names Protein Names

sodium/hydrogen exchanger 2

  • Na(+)/H(+) exchanger 2

Related Diseases

Diseases Alias
Diarrhea 1, Secretory Chloride, Congenital

  • DIAR1

  • Chloride Diarrhea, Congenital, Finnish Type

  • Congenital Secretory Chloride Diarrhea 1

  • Congenital Chloride Diarrhea Finnish Type

  • Congenital Chloride Diarrhea

  • Chloridorrhea, Congenital

  • Congenital Chloride Diarrhoea Finnish Type

  • Congenital Chloridorrhea

  • Congenital Secretory Chloride Diarrhoea 1

  • Chloridorrhea Congenital

  • Cld

  • Diarrhea 1 Secretory Chloride Congenital

  • Diarrhea, Type 1, Chloride, Secretory, Congenital
Short Bowel Syndrome

  • Short Gut Syndrome

  • Acquired Short Bowel Syndrome

  • Secondary Short Bowel Syndrome

  • Short Bowel Nos
Motility-Related Diarrhea
Spermatocele
Inflammatory Diarrhea
Osmotic Diarrhea
Secretory Diarrhea
Mucopolysaccharidosis, Type Ix

  • Mucopolysaccharidosis Type Ix

  • Hyaluronidase Deficiency

  • MPS9

  • Mps Ix

  • Mucopolysaccharidosis Ix

  • Mpsix

  • Mucopolysaccharidosis Type 9

  • Mucopolysaccharidosis 9
Diarrhea

  • Diarrhoea

  • Diarrhea Of Presumed Infectious Origin
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13342 SLC9A2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS13350 SLC9B2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus SLC9A2 VGNC VGNC:65432
Canis familiaris SLC9A2 VGNC VGNC:46484
Rattus norvegicus SLC9A2 RGD RGD:3719
Mus musculus SLC9A2 MGD MGI:105075
Macaca mulatta SLC9A2 VGNC VGNC:77637
Bos taurus SLC9A2 VGNC VGNC:34939