2. Gene
  3. SLC9A2 - solute carrier family 9 member A2 Gene

SLC9A2 - solute carrier family 9 member A2 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as NHE2

Gene ID: 6549 | Gene type: protein coding

About SLC9A2

Cytogenetic location: 2q12.1 Genomic coordinates (GRCh38): 2:102,619,553-102,711,355 (from NCBI)

This gene has 3 transcripts (splice variants), 233 orthologues and 10 paralogues. Biased expression in stomach (RPKM 13.9), colon (RPKM 13.0) and 10 other tissues.

Summary

This gene encodes a member of the sodium-hydrogen exchanger (NHE) protein family. These proteins are involved in sodium-ion transport by exchanging intracellular hydrogen ions to external sodium ions and help in the regulation of cell pH and volume. The encoded protein is localized to the apical membrane and is involved in apical absorption of sodium. [provided by RefSeq, Jun 2016]

SLC9A2 Products(1)

mRNA Protein Name
NM_003048.6 NP_003039.2 sodium/hydrogen exchanger 2 precursor

SLC9A2 Protein Structure

Na_H_Exchanger

Na_H_Exchanger: Sodium/hydrogen exchanger family (84 - 484)

  • 0
  • 200
  • 400
  • 600
  • 812 a.a.
Protein Preferred Names Protein Names

sodium/hydrogen exchanger 2

Na(+)/H(+) exchanger 2

Related Diseases

Diseases Alias
Diarrhea 1, Secretory Chloride, Congenital

DIAR1

Chloride Diarrhea, Congenital, Finnish Type

Congenital Secretory Chloride Diarrhea 1

Congenital Chloride Diarrhea Finnish Type

Congenital Chloride Diarrhea

Chloridorrhea, Congenital

Congenital Chloride Diarrhoea Finnish Type

Congenital Chloridorrhea

Congenital Secretory Chloride Diarrhoea 1

Chloridorrhea Congenital

Cld

Diarrhea 1 Secretory Chloride Congenital

Diarrhea, Type 1, Chloride, Secretory, Congenital
Short Bowel Syndrome

Short Gut Syndrome

Acquired Short Bowel Syndrome

Secondary Short Bowel Syndrome

Short Bowel Nos
Motility-Related Diarrhea
Spermatocele
Inflammatory Diarrhea
Osmotic Diarrhea
Secretory Diarrhea
Mucopolysaccharidosis, Type Ix

Mucopolysaccharidosis Type Ix

Hyaluronidase Deficiency

MPS9

Mps Ix

Mucopolysaccharidosis Ix

Mpsix

Mucopolysaccharidosis Type 9

Mucopolysaccharidosis 9
Diarrhea

Diarrhoea

Diarrhea Of Presumed Infectious Origin
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13342 SLC9A2 Human Pre-designed siRNA Set A / Unkown
HY-RS13350 SLC9B2 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus SLC9A2 VGNC VGNC:65432
Canis familiaris SLC9A2 VGNC VGNC:46484
Rattus norvegicus SLC9A2 RGD RGD:3719
Mus musculus SLC9A2 MGD MGI:105075
Macaca mulatta SLC9A2 VGNC VGNC:77637
Bos taurus SLC9A2 VGNC VGNC:34939