Eefsec - eukaryotic elongation factor, selenocysteine-tRNA-specific Gene
Also Known as sec; Selb; mSelB
Species: Mus musculus
Summary
Enables several functions, including GTP binding activity; GTPase activity; and RNA binding activity. Acts upstream of or within selenocysteine incorporation. Located in mitochondrion. Part of ribonucleoprotein complex. Orthologous to human EEFSEC (eukaryotic elongation factor, selenocysteine-tRNA specific). [provided by Alliance of Genome Resources, Apr 2022]
Eefsec Products (14)
| mRNA | Protein | Name |
|---|---|---|
| NM_001411439.1 | NP_001398368.1 | selenocysteine-specific elongation factor isoform 2 |
| NM_001411440.1 | NP_001398369.1 | selenocysteine-specific elongation factor isoform 3 |
| NM_001411441.1 | NP_001398370.1 | selenocysteine-specific elongation factor isoform 4 |
| NM_001411442.1 | NP_001398371.1 | selenocysteine-specific elongation factor isoform 5 |
| NM_001411443.1 | NP_001398372.1 | selenocysteine-specific elongation factor isoform 6 |
| NM_001411444.1 | NP_001398373.1 | selenocysteine-specific elongation factor isoform 7 |
| NM_001411445.1 | NP_001398374.1 | selenocysteine-specific elongation factor isoform 8 |
| NM_001411446.1 | NP_001398375.1 | selenocysteine-specific elongation factor isoform 9 |
| NM_001411447.1 | NP_001398376.1 | selenocysteine-specific elongation factor isoform 10 |
| NM_001411448.1 | NP_001398377.1 | selenocysteine-specific elongation factor isoform 11 |
| NM_001411449.1 | NP_001398378.1 | selenocysteine-specific elongation factor isoform 12 |
| NM_001411450.1 | NP_001398379.1 | selenocysteine-specific elongation factor isoform 13 |
| NM_001411451.1 | NP_001398380.1 | selenocysteine-specific elongation factor isoform 14 |
| NM_023060.4 | NP_075547.1 | selenocysteine-specific elongation factor isoform 1 |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables GTP binding |
IDA
IDA: Inferred from direct assay
|
10970870 | MGI |
| enables GTPase activity |
IDA
IDA: Inferred from direct assay
|
22992746 | MGI |
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
22992746 | MGI |
| enables ribonucleoprotein complex binding |
IDA
IDA: Inferred from direct assay
|
22992746 | MGI |
| enables selenocysteine insertion sequence binding |
IDA
IDA: Inferred from direct assay
|
22992746 | MGI |
| enables tRNA binding |
IDA
IDA: Inferred from direct assay
|
10970870 | MGI |
| enables translation elongation factor activity |
IDA
IDA: Inferred from direct assay
|
22992746 | MGI |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| acts upstream of or within selenocysteine incorporation |
IDA
IDA: Inferred from direct assay
|
10970870 | MGI |
| acts upstream of or within selenocysteine incorporation |
IMP
IMP: Inferred from mutant phenotype
|
10992298 | MGI |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| part of ribonucleoprotein complex |
IDA
IDA: Inferred from direct assay
|
22992746 | MGI |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
selenocysteine-specific elongation factor |
|