Eefsec - eukaryotic elongation factor, selenocysteine-tRNA-specific Gene

Mus musculus

Also known as sec; Selb; mSelB

Gene ID: 65967 | Gene type: protein coding

About Eefsec

Summary

Enables several functions, including GTP binding activity; GTPase activity; and RNA binding activity. Acts upstream of or within selenocysteine incorporation. Located in mitochondrion. Part of ribonucleoprotein complex. Orthologous to human EEFSEC (eukaryotic elongation factor, selenocysteine-tRNA specific). [provided by Alliance of Genome Resources, Apr 2022]

Eefsec Products(14)

mRNA	Protein	Name
NM_001411439.1	NP_001398368.1	selenocysteine-specific elongation factor isoform 2
NM_001411440.1	NP_001398369.1	selenocysteine-specific elongation factor isoform 3
NM_001411441.1	NP_001398370.1	selenocysteine-specific elongation factor isoform 4
NM_001411442.1	NP_001398371.1	selenocysteine-specific elongation factor isoform 5
NM_001411443.1	NP_001398372.1	selenocysteine-specific elongation factor isoform 6
NM_001411444.1	NP_001398373.1	selenocysteine-specific elongation factor isoform 7
NM_001411445.1	NP_001398374.1	selenocysteine-specific elongation factor isoform 8
NM_001411446.1	NP_001398375.1	selenocysteine-specific elongation factor isoform 9
NM_001411447.1	NP_001398376.1	selenocysteine-specific elongation factor isoform 10
NM_001411448.1	NP_001398377.1	selenocysteine-specific elongation factor isoform 11
NM_001411449.1	NP_001398378.1	selenocysteine-specific elongation factor isoform 12
NM_001411450.1	NP_001398379.1	selenocysteine-specific elongation factor isoform 13
NM_001411451.1	NP_001398380.1	selenocysteine-specific elongation factor isoform 14
NM_023060.4	NP_075547.1	selenocysteine-specific elongation factor isoform 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables GTP binding	IDA IDA: Inferred from direct assay	10970870	MGI
enables GTPase activity	IDA IDA: Inferred from direct assay	22992746	MGI
enables protein binding	IPI IPI: Inferred from physical interaction	22992746	MGI
enables ribonucleoprotein complex binding	IDA IDA: Inferred from direct assay	22992746	MGI
enables selenocysteine insertion sequence binding	IDA IDA: Inferred from direct assay	22992746	MGI
enables tRNA binding	IDA IDA: Inferred from direct assay	10970870	MGI
enables translation elongation factor activity	IDA IDA: Inferred from direct assay	22992746	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within selenocysteine incorporation	IDA IDA: Inferred from direct assay	10970870	MGI
acts upstream of or within selenocysteine incorporation	IMP IMP: Inferred from mutant phenotype	10992298	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
part of ribonucleoprotein complex	IDA IDA: Inferred from direct assay	22992746	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

selenocysteine-specific elongation factor

MJ0495-like protein SelB

elongation factor sec

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04182	EEFSEC Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Eefsec	NCBI	NCBI:60678

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