EEFSEC - eukaryotic elongation factor, selenocysteine-tRNA specific Gene
Also Known as SELB; EFSEC
Species: Homo sapiens
About EEFSEC
This gene has 4 transcripts (splice variants), 1 gene allele, 197 orthologues and 18 paralogues. Ubiquitous expression in testis (RPKM 3.1), kidney (RPKM 2.8) and 25 other tissues.
Summary
Predicted to enable translation elongation factor activity. Predicted to be involved in selenocysteine incorporation. Predicted to be located in cytoplasm and nucleus. Predicted to be part of ribonucleoprotein complex. [provided by Alliance of Genome Resources, Apr 2022]
EEFSEC Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_021937.5 | NP_068756.2 | selenocysteine-specific elongation factor |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables GTPase activity |
IDA
IDA: Inferred from direct assay
|
27708257 | GOA |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| involved in selenocysteine incorporation |
IDA
IDA: Inferred from direct assay
|
27708257 | GOA |
EEFSEC Protein Structure
GTP_EFTU: Elongation factor Tu GTP binding domain (7 - 212)
GTP_EFTU_D2: Elongation factor Tu domain 2 (238 - 291)
- 0
- 100
- 200
- 300
- 400
- 500
- 596 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
selenocysteine-specific elongation factor |
|
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Keshan Disease |
|
|
| Colorado Tick Fever |
|
|
| Rigid Spine Muscular Dystrophy 1 |
|
|
Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Rattus norvegicus | EEFSEC | RGD | RGD:1560552 |
| Macaca mulatta | EEFSEC | VGNC | VGNC:72097 |
| Bos taurus | EEFSEC | VGNC | VGNC:28337 |
| Felis catus | EEFSEC | VGNC | VGNC:61735 |
| Mus musculus | EEFSEC | MGD | MGI:2137092 |
| Canis familiaris | EEFSEC | VGNC | VGNC:40211 |
| Others | EEFSEC | NCBI |