Setd6 - SET domain containing 6 Gene

Also Known as 0610039J04Rik; 3110004G14Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 66083

Summary

Predicted to enable NF-kappaB binding activity; S-adenosyl-L-methionine binding activity; and protein-lysine N-methyltransferase activity. Involved in stem cell differentiation and stem cell population maintenance. Predicted to be located in chromosome; cytosol; and nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and neural retina. Orthologous to several human genes including SETD6 (SET domain containing 6, protein lysine methyltransferase). [provided by Alliance of Genome Resources, Apr 2022]

Setd6 Products (2)

mRNA Protein Name
NM_001035123.4 NP_001030295.1 N-lysine methyltransferase SETD6 isoform 1
NM_001368354.1 NP_001355283.1 N-lysine methyltransferase SETD6 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
26275350 MGI
Biological Process GO Annotation Evidence References Source
involved in stem cell differentiation IDA
IDA: Inferred from direct assay
23324626 MGI
involved in stem cell population maintenance IDA
IDA: Inferred from direct assay
23324626 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

N-lysine methyltransferase SETD6

  • SET domain-containing protein 6

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12746 SETD6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21697 Prex1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Setd6 NCBI NCBI:79918