Nova1 - NOVA alternative splicing regulator 1 Gene

Also Known as Nova-1; G630039L02; 9430099M15Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 664883

Summary

Enables mRNA 3'-UTR binding activity and sequence-specific mRNA binding activity. Involved in negative regulation of cold-induced thermogenesis and regulation of alternative mRNA splicing, via spliceosome. Acts upstream of or within mRNA splicing, via spliceosome and regulation of RNA metabolic process. Located in nucleus. Is expressed in several structures, including nervous system and retina. Orthologous to human NOVA1 (NOVA alternative splicing regulator 1). [provided by Alliance of Genome Resources, Apr 2022]

Nova1 Products (14)

mRNA Protein Name
NM_001364634.1 NP_001351563.1 RNA-binding protein Nova-1 isoform 2
NM_001364635.1 NP_001351564.1 RNA-binding protein Nova-1 isoform 3
NM_001364636.1 NP_001351565.1 RNA-binding protein Nova-1 isoform 4
NM_001364637.1 NP_001351566.1 RNA-binding protein Nova-1 isoform 4
NM_001364638.1 NP_001351567.1 RNA-binding protein Nova-1 isoform 5
NM_001364639.1 NP_001351568.1 RNA-binding protein Nova-1 isoform 6
NM_021361.2 NP_067336.1 RNA-binding protein Nova-1 isoform 1
NM_001364634.1 NP_001351563.1 RNA-binding protein Nova-1 isoform 2
NM_001364635.1 NP_001351564.1 RNA-binding protein Nova-1 isoform 3
NM_001364636.1 NP_001351565.1 RNA-binding protein Nova-1 isoform 4
NM_001364637.1 NP_001351566.1 RNA-binding protein Nova-1 isoform 4
NM_001364638.1 NP_001351567.1 RNA-binding protein Nova-1 isoform 5
NM_001364639.1 NP_001351568.1 RNA-binding protein Nova-1 isoform 6
NM_021361.2 NP_067336.1 RNA-binding protein Nova-1 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables RNA binding IDA
IDA: Inferred from direct assay
8558240 MGI
enables mRNA 3'-UTR binding IDA
IDA: Inferred from direct assay
27378374 MGI
enables mRNA binding IDA
IDA: Inferred from direct assay
10719891 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
10829067 MGI
enables sequence-specific mRNA binding IDA
IDA: Inferred from direct assay
9154818 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within mRNA splicing, via spliceosome IDA
IDA: Inferred from direct assay
10719891 MGI
acts upstream of or within mRNA splicing, via spliceosome IMP
IMP: Inferred from mutant phenotype
10719891 MGI
involved in negative regulation of cold-induced thermogenesis IGI
IGI: Inferred from genetic interaction
27635635 MGI
acts upstream of or within regulation of RNA metabolic process IGI
IGI: Inferred from genetic interaction
23359859 MGI
involved in regulation of alternative mRNA splicing, via spliceosome IDA
IDA: Inferred from direct assay
17065982 MGI
involved in regulation of alternative mRNA splicing, via spliceosome IMP
IMP: Inferred from mutant phenotype
14615540 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
8558240 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

RNA-binding protein Nova-1

  • neuro-oncological ventral antigen 1

  • ventral neuron-specific protein 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09455 NOVA1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nova1 NCBI NCBI:4857