Spag16 - sperm associated antigen 16 Gene

Also Known as Pf20; Wdr29; 4921511D23Rik; 4930524F24Rik; 4930585K05Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 66722

Summary

Enables protein kinase binding activity. Involved in cilium assembly. Acts upstream of or within several processes, including cell motility in response to calcium ion; epithelial cilium movement involved in extracellular fluid movement; and sperm axoneme assembly. Located in cytoskeleton; nucleus; and sperm flagellum. Orthologous to human SPAG16 (sperm associated antigen 16). [provided by Alliance of Genome Resources, Apr 2022]

Spag16 Products (3)

mRNA Protein Name
NM_001271533.1 NP_001258462.1 sperm-associated antigen 16 protein isoform 3
NM_025728.4 NP_080004.1 sperm-associated antigen 16 protein isoform 2
NM_029160.3 NP_083436.2 sperm-associated antigen 16 protein isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
12391165 MGI
enables protein kinase binding IPI
IPI: Inferred from physical interaction
18367677 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within cerebrospinal fluid circulation IGI
IGI: Inferred from genetic interaction
17323374 MGI
involved in cilium assembly IDA
IDA: Inferred from direct assay
19305393 MGI
acts upstream of or within mucociliary clearance IGI
IGI: Inferred from genetic interaction
17323374 MGI
acts upstream of or within sperm axoneme assembly IMP
IMP: Inferred from mutant phenotype
15328412 MGI
Cellular Component GO Annotation Evidence References Source
located in axonemal central apparatus IDA
IDA: Inferred from direct assay
12391165 MGI
located in axoneme IDA
IDA: Inferred from direct assay
19305393 MGI
located in sperm flagellum IDA
IDA: Inferred from direct assay
27682589 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sperm-associated antigen 16 protein

  • pf20 protein homolog

  • sperm-associated WD repeat protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13621 SPAG16 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Spag16 NCBI NCBI:79582