2. Gene
  3. Serbp1 - serpine1 mRNA binding protein 1 Gene

Serbp1 - serpine1 mRNA binding protein 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Pairbp1; 1200009K13Rik; 9330147J08Rik

Gene ID: 66870 | Gene type: protein coding

About Serbp1

Summary

Predicted to enable SUMO binding activity; mRNA 3'-UTR binding activity; and ribosome binding activity. Predicted to be involved in PML body organization and regulation of apoptotic process. Predicted to be located in cytosol and plasma membrane. Predicted to be active in cytoplasm and nucleus. Is expressed in early conceptus; oocyte; ovary; and ovary stratum granulosum. Orthologous to human SERBP1 (SERPINE1 mRNA binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Serbp1 Products(4)

mRNA Protein Name
NM_001113564.1 NP_001107036.1 plasminogen activator inhibitor 1 RNA-binding protein isoform 2
NM_001113565.1 NP_001107037.1 plasminogen activator inhibitor 1 RNA-binding protein isoform 3
NM_001113566.1 NP_001107038.1 plasminogen activator inhibitor 1 RNA-binding protein isoform 4
NM_025814.2 NP_080090.2 plasminogen activator inhibitor 1 RNA-binding protein isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables ribosome binding IDA
IDA: Inferred from direct assay
34815424 MGI
enables translation elongation factor binding IDA
IDA: Inferred from direct assay
34815424 MGI
enables translation repressor activity IDA
IDA: Inferred from direct assay
34815424 MGI
Biological Process GO Annotation Evidence Reference Source
involved in negative regulation of translation IDA
IDA: Inferred from direct assay
34815424 MGI
involved in ribosome hibernation IDA
IDA: Inferred from direct assay
34815424 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

plasminogen activator inhibitor 1 RNA-binding protein

PAI-1 mRNA-binding protein

PAI-RBP1

PAI1 RNA-binding protein 1

SERPINE1 mRNA-binding protein 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12687 SERBP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Serbp1 NCBI NCBI:26135