Shisa5 - shisa family member 5 Gene

Also Known as Scotin; mShisa5; 2310008D10Rik; 6430628I05Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 66940

Summary

Predicted to enable WW domain binding activity. Acts upstream of or within intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator. Located in endoplasmic reticulum and nuclear envelope. Is expressed in chorion; extraembryonic ectoderm; foregut diverticulum; and yolk sac. Orthologous to human SHISA5 (shisa family member 5). [provided by Alliance of Genome Resources, Apr 2022]

Shisa5 Products (12)

mRNA Protein Name
NM_001284332.1 NP_001271261.1 protein shisa-5 isoform 3 precursor
NM_001357932.1 NP_001344861.1 protein shisa-5 isoform 4
NM_001357933.1 NP_001344862.1 protein shisa-5 isoform 5
NM_001357934.1 NP_001344863.1 protein shisa-5 isoform 6
NM_001357935.1 NP_001344864.1 protein shisa-5 isoform 7
NM_001357936.1 NP_001344865.1 protein shisa-5 isoform 7
NM_001357937.1 NP_001344866.1 protein shisa-5 isoform 7
NM_001357939.1 NP_001344868.1 protein shisa-5 isoform 7
NM_001357940.1 NP_001344869.1 protein shisa-5 isoform 7
NM_001357941.1 NP_001344870.1 protein shisa-5 isoform 7
NM_025858.3 NP_080134.1 protein shisa-5 isoform 1 precursor
NM_026381.5 NP_080657.1 protein shisa-5 isoform 2

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within intrinsic apoptotic signaling pathway by p53 class mediator IMP
IMP: Inferred from mutant phenotype
12135983 MGI
acts upstream of or within intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator IDA
IDA: Inferred from direct assay
12135983 MGI
Cellular Component GO Annotation Evidence References Source
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
12135983 MGI
located in nuclear envelope IDA
IDA: Inferred from direct assay
12135983 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein shisa-5

  • shisa homolog 5

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12868 SHISA5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Shisa5 NCBI NCBI:51246