Mboat2 - membrane bound O-acyltransferase domain containing 2 Gene

Also Known as Oact2; LPCAT4; Moact2; 2810049G06Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 67216

Summary

Enables 1-acylglycerophosphocholine O-acyltransferase activity and 1-acylglycerophosphoethanolamine O-acyltransferase activity. Involved in phosphatidylcholine acyl-chain remodeling; phosphatidylethanolamine acyl-chain remodeling; and regulation of chondrocyte differentiation. Located in endoplasmic reticulum membrane. Is expressed in several structures, including T1 rib costal cartilage; alimentary system; genitourinary system; nervous system; and respiratory system. Orthologous to human MBOAT2 (membrane bound O-acyltransferase domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]

Mboat2 Products (2)

mRNA Protein Name
NM_001083341.1 NP_001076810.1 lysophospholipid acyltransferase 2 isoform b
NM_026037.3 NP_080313.2 lysophospholipid acyltransferase 2 isoform a

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables 1-acylglycerophosphocholine O-acyltransferase activity IDA
IDA: Inferred from direct assay
18287005 MGI
enables 1-acylglycerophosphocholine O-acyltransferase activity IMP
IMP: Inferred from mutant phenotype
29196633 MGI
enables 1-acylglycerophosphoethanolamine O-acyltransferase activity IDA
IDA: Inferred from direct assay
18287005 MGI
Biological Process GO Annotation Evidence References Source
involved in phosphatidylcholine acyl-chain remodeling IMP
IMP: Inferred from mutant phenotype
18287005 MGI
involved in phosphatidylethanolamine acyl-chain remodeling IMP
IMP: Inferred from mutant phenotype
18287005 MGI
involved in regulation of chondrocyte differentiation IMP
IMP: Inferred from mutant phenotype
29196633 MGI
Cellular Component GO Annotation Evidence References Source
located in endoplasmic reticulum membrane IDA
IDA: Inferred from direct assay
18287005 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

lysophospholipid acyltransferase 2

  • 1-acylglycerophosphocholine O-acyltransferase

  • 1-acylglycerophosphoethanolamine O-acyltransferase

  • LPC acyltransferase 4

  • LPCAT

  • LPEAT

  • LPLAT 2

  • O-acyltransferase (membrane bound) domain containing 2

  • O-acyltransferase domain-containing protein 2

  • lyso-PC

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08194 MBOAT2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mboat2 NCBI NCBI:129642