Plekho1 - pleckstrin homology domain containing, family O member 1 Gene

Also Known as Jza2; Ckip1; CKIP-1; JZA-20; 2810052M02Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 67220

Summary

Acts upstream of or within several processes, including lamellipodium morphogenesis; myoblast fusion; and myoblast migration. Located in muscle cell projection membrane and ruffle membrane. Orthologous to human PLEKHO1 (pleckstrin homology domain containing O1). [provided by Alliance of Genome Resources, Apr 2022]

Plekho1 Products (1)

mRNA Protein Name
NM_023320.2 NP_075809.1 pleckstrin homology domain-containing family O member 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
22553210 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within lamellipodium morphogenesis IDA
IDA: Inferred from direct assay
22553210 MGI
acts upstream of or within lamellipodium morphogenesis IMP
IMP: Inferred from mutant phenotype
22553210 MGI
acts upstream of or within myoblast fusion IDA
IDA: Inferred from direct assay
22553210 MGI
acts upstream of or within myoblast fusion IMP
IMP: Inferred from mutant phenotype
22553210 MGI
acts upstream of or within myoblast migration IMP
IMP: Inferred from mutant phenotype
22553210 MGI
acts upstream of or within regulation of cell shape IDA
IDA: Inferred from direct assay
22553210 MGI
acts upstream of or within regulation of cell shape IMP
IMP: Inferred from mutant phenotype
22553210 MGI
Cellular Component GO Annotation Evidence References Source
located in muscle cell projection membrane IDA
IDA: Inferred from direct assay
22553210 MGI
located in ruffle membrane IDA
IDA: Inferred from direct assay
22553210 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

pleckstrin homology domain-containing family O member 1

  • CK2 interacting protein 1

  • Jun zipper-associated 2

  • PH domain-containing family O member 1

  • TNF intracellular domain-interacting protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10700 PLEKHO1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Plekho1 NCBI NCBI:51177