PLEKHO1 - pleckstrin homology domain containing O1 Gene

Also Known as JBP; CKIP1; OC120; CKIP-1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 51177

About PLEKHO1

Cytogenetic location: 1q21.2 Genomic coordinates (GRCh38): 1:150,149,646-150,160,065 (from NCBI)

This gene has 9 transcripts (splice variants), 197 orthologues and 1 paralogue. Broad expression in testis (RPKM 30.7), appendix (RPKM 29.1) and 24 other tissues.

Summary

Predicted to act upstream of or within several processes, including lamellipodium morphogenesis; myoblast fusion; and myoblast migration. Predicted to be located in cell projection membrane; cytoplasm; and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

PLEKHO1 Products (4)

mRNA Protein Name
NM_001304722.2 NP_001291651.1 pleckstrin homology domain-containing family O member 1 isoform b
NM_001304723.2 NP_001291652.1 pleckstrin homology domain-containing family O member 1 isoform b
NM_001304724.2 NP_001291653.1 pleckstrin homology domain-containing family O member 1 isoform c
NM_016274.6 NP_057358.2 pleckstrin homology domain-containing family O member 1 isoform a

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
20580715 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PLEKHO1 Protein Structure

PH

PH: PH domain (24 - 131)

  • 0
  • 100
  • 200
  • 300
  • 409 a.a.
Protein Preferred Names Protein Names

pleckstrin homology domain-containing family O member 1

  • C-Jun-binding protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10700 PLEKHO1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus PLEKHO1 RGD RGD:1311487
Mus musculus PLEKHO1 MGD MGI:1914470
Canis familiaris PLEKHO1 VGNC VGNC:44687
Felis catus PLEKHO1 VGNC VGNC:80309
Bos taurus PLEKHO1 VGNC VGNC:33026
Macaca mulatta PLEKHO1 VGNC VGNC:76101
Others PLEKHO1 NCBI